Studying Warmed Lidocaine for Increased Analgesic Effect During Intravitreal Injections

Comparing the Anesthetic Effect of Warmed Lidocaine to Room Temperature Lidocaine When Applied Topically for Intravitreal Injections

Status

Terminated

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06962709

Acronym

WarmLido

Enrollment

100

Registered

2025-05-08

Start date

2024-06-12

Completion date

2026-05-01

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain Intensity Assessment, Pain Management

Keywords

warmed lidocaine, intravitreal injections

Brief summary

Investigating whether warmed lidocaine increases analgesic effect for intravitreal injections

Interventions

OTHERWarmed lidocaine

Lidocaine warmed to 98 F

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

OTHER

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Receiving intravitreal injection for any indication

Exclusion criteria

* Previous participant in study

Design outcomes

Primary

Measure	Time frame	Description
Pain Rating	immediately after the intervention	The level of pain associated with intravitreal injection as marked by patient on 10cm line.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 15, 2026