Energy Expenditure, Metabolic Regulation
Conditions
Keywords
Intermittent running, Energy expenditure
Brief summary
The purpose of this study is to investigate the suitability of intermittent exercise of long and short intervals at lower intensities than HIIE on energy expenditure during and post-exercise compared to MICE, as well as determine whether similar or greater effects can be achieved for glycemic control in recreationally active adults.
Detailed description
The same procedure will be repeated for all trials: Participants will be asked to perform 3 trials in a randomized-crossover design \[moderate-intensity continuous running (MICE: 60% V̇O2max), 5-minute interval running (5MIN; 50% and 70% V̇O2max), 2-minute interval running (2MIN; 50% and 70% V̇O2max)\]. All trials will be separated by at least 4 days wash-out and less than 14 days between trials to ensure complete rest. Sensors for measuring muscle oxygen (10 cm proximal to the mid-patella, and 2 cm lateral) will be placed on the rectus femoris muscle and 15 min resting metabolic rate was measured. After baseline measurements, participants warm-up for 3 minutes with fixed walking intensity (i.e., 5 km/h) followed by 40 minutes running. Immediately after the running, participants return to a seated position for 30 minutes post-exercise measurements (EPOC). During the EPOC and resting metabolic rate (RMR) measurement participants will sit in a comfortable position and need to limit fidgeting, thus allowed only to watch TV or videos on their phone. Participants will be wheeled to the bathroom if needed.
Interventions
BEHAVIORALModerate-intensity continuous running (MICE: 60% V̇O2max)
Participants run continuously for 40 minutes at moderate intensity (60-65% V̇O2max)
BEHAVIORAL5-minute interval running (5MIN)
Participants run for 40 minutes at average moderate intensity with 5-minutes slow and fast cycles where speed is increased and decreased by 20%.
BEHAVIORAL2-minute interval running (2MIN)
Participants run for 40 minutes at average moderate intensity with 2-minutes slow and fast cycles where speed is increased and decreased by 20%.
Sponsors
National Taiwan Normal University
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Participants will be asked to perform 4 trials in a randomized-crossover design (1) moderate-intensity continuous running (MICE: 60% V̇O2max), (2) 5-minute interval running (5MIN; 50% and 70% V̇O2max), (3) 2-minute interval running (2MIN; 50% and 70% V̇O2max).
Eligibility
Sex/Gender
MALE
Age
20 Years to 45 Years
Healthy volunteers
Yes
Inclusion criteria
* Healthy recreationally active men * BMI between 18.5-27 kg/m2 * Aged between 20 to 45 years * Regular exercise (3 times per week and longer than 3 months) with cardio exercise longer than 30 minutes at least once a week * Weight stable for more than 3 months (no change in weight +/- 3%) * Non-shift workers and sleep at least 6.5-9 hours for the past 3 months * Non-smoker
Exclusion criteria
* having any cardiovascular, metabolic or pulmonary disease (angina pectoris or uncontrolled arrhythmias) * suffering from infectious contagious diseases, * using medications that could affect metabolic responses (including anti-inflammatory medications) * smoking * heavy alcohol intake (more than 4 drinks on any day or more than 14 drinks a week). * undergoing special diets (e.g., intermittent fasting and/or ketogenic diets)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Total energy expenditure | 70 minutes | Changes in total energy expenditure during 40-minutes running and 30 minutes of EPOC |
| Substrate utilisation | 70 minutes | Changes in substrate utilisation during 40-minutes running and 30 minutes of EPOC |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscle oxygen saturation | 70 minutes | Changes in muscle oxygen during 40 minutes running and 30 minutes EPOC |
| Subjective appetite sensation | 70 minutes | Changes in subjective feeling of appetite using 0-100 mm scale (e.g., hunger and satisfaction) during trials |
Countries
Taiwan
Contacts
CONTACTYung-Chih Chen, PhD
Outcome results
None listed