Establishment of a Longitudinal Cohort for Newborns With Low Apgar Scores at Birth

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06961123

Enrollment

600

Registered

2025-05-07

Start date

2025-03-11

Completion date

2027-12-31

Last updated

2025-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low Apgar Scores

Keywords

Low Apgar scores, neonatal, birth cohort

Brief summary

The objective of this study is to identify high-risk factors associated with low Apgar scores, implement proactive interventions to reduce their occurrence, and analyze neonatal resuscitation procedures and systemic treatment during hospitalization. This aims to provide evidence-based references for improving the resuscitation and medical management of newborns with low Apgar scores, thereby enhancing clinical care capabilities. Additionally, continuous follow-up management and timely intervention guidance will be provided to these infants to optimize their long-term prognosis.

Detailed description

This is a prospective and retrospective biphasic cohort study.Retrospective cohort inclusion criteria: Newborns born between January 1, 2006 and before the start of the project at Peking University Third Hospital with Apgar scores ≤ 7 at 1 minute, 5 minutes, or 10 minutes. Prospective cohort inclusion criteria: Newborns born in our hospital between the start of the project and December 31, 2027, with an Apgar score of ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Retrospective cohort inclusion criteria: Newborns born between January 1, 2006 and before the start of the project at Peking University Third Hospital with Apgar scores ≤ 7 at 1 minute, 5 minutes, or 10 minutes. Prospective cohort inclusion criteria: Newborns born at Peking University Third Hospital between the start of the project and December 31, 2027, with an Apgar score of ≤ 7 at 1 minute, 5 minutes, or 10 minutes.

Exclusion criteria

* There are serious congenital malformations that affect physical and neurological development, and family members refuse to participate in the study

Design outcomes

Primary

Measure	Time frame	Description
Physical development indicators, Neurodevelopmental outcome	6 months old, 1 year old, 2 years old	Physical development indicators：height, weight, head circumference, BMI, Z-score Neurodevelopmental outcome: Good neural development, poor neural development, cerebral palsy, autism spectrum disorder, Attention deficit hyperactivity disorder

Countries

China

Contacts

Primary Contactqingqing wang

wangqing01s@163.com86+15101020751

Outcome results