Aphthous Stomatitis, Aphthous Stomatitis, Recurrent, Aphthous Ulcer
Conditions
Keywords
Alum stone, aphthous ulcer, mucosal adhesive patches
Brief summary
The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition. The experimental group was administered 1x1cm mucosal patches containing alum stone at a concentration of 7%, whereas the control group was given placebo patches without any active medication. Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5. Statistical analysis was performed with repeated measures ANOVA using R software.
Detailed description
The study's results indicated that the utilization of alum stone in mucosal adhesive patches yielded significant reductions in size of aphthous lesions and degree of pain.
Interventions
PROCEDURESize of aphthous lesions and degree of pain assessed at days 1, 3, and 5.
Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5.
PROCEDUREControl
The dimensions of the lesion were measured by oral medicine specialists using a flexible ruler
DEVICEALUMSTONE
alum administration via adhesive patches on the healing process of aphthous ulcers
Sponsors
University Of Anbar
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Intervention model description
In this study one hundred female, aged between twenty-two and thirty years, reported multiple oral aphthous ulcers. The evaluation of recurrent aphthous stomatitis (RAS) was performed by an oral medicine specialist, who relied on the clinical manifestations of the condition. The experimental group was administered 1x1cm mucosal patches containing alum stone at a concentration of 7%, whereas the control group was given placebo patches without any active medication. Size of aphthous lesions and degree of pain assessed at days 1, 3, and 5. Statistical analysis was performed with repeated measures ANOVA using R software
Eligibility
Sex/Gender
FEMALE
Age
22 Years to 35 Years
Healthy volunteers
Yes
Inclusion criteria
individuals who had a history of RAS, with oral ulceration occurring at least once a month and persistent oral ulceration being present in the majority of patients. Additionally, individuals with mild aphthous ulcer, characterized by ulcer development lasting fewer than three days, were also included. \-
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lesion Size | 1, 3, 5 day |
Countries
Iraq
Outcome results
None listed