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Postoperative Atrial Fibrillation in Cardiac Surgery

Incidence and Risk Factors of Postoperative Atrial Fibrillation in Cardiac Surgery Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06958029
Acronym
POAF
Enrollment
275
Registered
2025-05-06
Start date
2025-04-01
Completion date
2025-06-10
Last updated
2025-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-operative Atrial Fibrillation

Keywords

postoperative, atrial fibrillation, cardiac surgery

Brief summary

This multicenter observational study aims to investigate the incidence and identify risk factors associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac surgery at three medical centers in Thailand. The study will examine patient characteristics, surgical factors, and anesthetic management practices that may contribute to the development of this common postoperative complication.

Detailed description

Postoperative atrial fibrillation (POAF) is a common complication following cardiac surgery, with incidence rates reported between 15-30% after valve surgery and 18-74% after coronary artery bypass grafting. POAF typically occurs within 72 hours after surgery and is associated with increased morbidity, mortality, length of hospital stay, and healthcare costs. The Society of Thoracic Surgeons has identified five major postoperative complications associated with cardiac surgery, including POAF, which can significantly affect patient outcomes. This multicenter observational study will examine the incidence and risk factors of POAF in cardiac surgery patients across three medical centers in Thailand: Srinagarind Hospital at Khon Kaen University, Northeastern Thailand Cardiac Center, and Surat Thani Hospital. The study will collect data on patient demographics, comorbidities, preoperative laboratory values, perioperative characteristics, surgical procedures (valve surgery, CABG, combined procedures), and postoperative complications. By identifying risk factors associated with POAF, this study aims to develop preventive strategies and improve management protocols for patients at high risk for this complication.

Interventions

PROCEDURECardiac surgery

Patients receiving general anesthesia for cardiac surgery

Sponsors

Khon Kaen University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Age ≥ 18 years * Patients undergoing cardiac valve surgery or coronary artery bypass grafting (CABG) procedures

Exclusion criteria

* Patients undergoing aortic surgery * Patients undergoing MAZE procedure * Incomplete medical records * Patients who required mechanical circulatory support before surgery * Patients who died during surgery or within 3 days after surgery

Design outcomes

Primary

MeasureTime frameDescription
Incidence72 hours postoperativelyThe incidence of POAF

Secondary

MeasureTime frameDescription
Risk factors72 hours postoperativelyRisk factors associated with POAF

Countries

Thailand

Contacts

Primary ContactSirirat Tribuddharat, MD, PhD
sirirat.tribuddharat@gmail.com66-81-6205921

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026