Wound, Infection Prevention, Negative Pressure Wound Therapy
Conditions
Brief summary
Total 70 participants meeting selection criteria will be enrolled in the study from operational theatre. They will be randomly divided in two groups by using lottery method. In group A, Negative Pressure Wound Therapy will be applied at end of procedure. In group B, no Negative Pressure Wound Therapy will be placed. They will be shifted to post-surgical wad for 72 hours and then will be discharged with prescription of standard antibiotics and will be followed-up in OPD for 30 days. If patient will develop surgical site wound infection, then it will be noted. If infection will not be cured with antibiotics course, then re-operation will be done. Patients complications will be managed as per hospital protocol. All this information will be recorded in proforma.
Interventions
OTHERNegative Pressure Wound Therapy
Negative Pressure Wound Therapy is an intervention in which a suction is applied at applied thus creating a negative pressure which not only removes any exudate but also aids in formation of granulation tissue. NPWT is provided along with empirical prophylactic antibiotics
According to hospital antibiogram, empirical antibiotics are given prophylactically
Sponsors
Dr Hamail Khanum
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Patients of age between 20 to 70 years, both genders * Undergoing laparotomy under general anaesthesia * ASA I-II
Exclusion criteria
* Patients who did not complete the follow up instructions * Pregnant patients * Patients already undergone a relook laparotomy, if their abdomen is left open or if unable to adhere
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Surgical Site Infection | 03 Months | It will be labelled if there will be presence of pus and pus discharge from wound site, confirmation of presence of pathogen through culture along with presence of pain, swelling, tenderness at wound site on physical examination during 15-30 days of surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Re Operation | 03 Months | It will be labelled if patient will undergo surgery due to severe surgical site wound infection that develop during 15-30 days of surgery and not healed with antibiotics course. |
Countries
Pakistan
Contacts
Primary ContactDr Hamail Khanum, MBBS
Outcome results
None listed