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TCI vs. Manuel TIVA in Septorhinoplasty Surgeries

Comparison of the Effects in Target-controlled and Manually Controlled Total Intravenous Anesthesia on Postoperative Recovery and Patient Quality of Recovery in Septorhinoplasty Surgeries

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06957470
Enrollment
80
Registered
2025-05-04
Start date
2025-04-01
Completion date
2026-12-01
Last updated
2025-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia

Keywords

septorhinoplasty, TIVA (total intravenous anesthesia), TCI (target controlled infusion)

Brief summary

Septorhinoplasty is a surgical technique that can be used to correct various nasal deformities.Total intravenous anesthesia (TIVA) is a frequently preferred method as an anesthesia technique in septorhinoplasty surgeries.It has been reported that TIVA reduces the incidence of postoperative nausea and vomiting, is more successful in acute postoperative pain control compared to inhalational anesthesia, provides more stable hemodynamics, provides quicker awakening after anesthesia, is more effective in preventing recovery agitation and cough, and is effective in controlled hypotension.

Interventions

PROCEDURETotal Intravenous Anesthesia

It is a general anesthesia technique performed through a combination of intravenous agents administered intravenously by various methods.

Sponsors

Bulent Ecevit University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes

Inclusion criteria

* Patients aged 18-65 years with American Society of Anesthesiology (ASA) physical status I-II who will undergo Septorhinoplasty Surgery under general anesthesia will be included in the study.

Exclusion criteria

Patients who do not agree to participate in the study Patients under 18 and over 65 Patients with ASA score III and above Clinical diagnosis of neuropsychiatric disorders Those with a history of chronic NSAID, tranquilizer, opioid or sleeping pill use Clinical diagnosis of Serious cardiac diseases Clinical diagnosis of central-autonomic nervous system disease Clinical diagnosis of Coagulopathy Those with soybean oil allergy and a history of allergy to any study drug BMI \>30 kg m2, pregnancy breastfeeding patients

Design outcomes

Primary

MeasureTime frameDescription
postoperative recoveryat postoperative 6 hours and 24 hoursPostoperative recovery will evaluate with quality of recovery-40 questionnaire. quality of recovery-40 scores range from 40 (extremely poor quality of recovery) to 200 (excellent quality of recovery).
agitation during emergencePostoperative 0 and 15. Minutes at the recovery roomAgitation will evaluate with richmond sedation agitation scale. The richmond sedation agitation scale is a 10-point scale ranging from -5 to +4. Levels -1 to -5 denote 5 levels of sedation, starting with awakens to voice and ending with unarousable. Levels +1 to +4 describe increasing levels of agitation.

Secondary

MeasureTime frameDescription
surgeon satisfactionat the end of surgery5-point Likert Scale
postoperative painat the end of the surgeryNumeric Rating Scale at the PACU
nausea and vomitingPostoperative 0 hours at recovery room4-point Likert Scale

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026