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Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume

Effects of Surgical Correction of Nasal Obstruction on Oxygen Uptake and Ventilation Volume

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06957262
Enrollment
22
Registered
2025-05-04
Start date
2017-01-01
Completion date
2020-01-15
Last updated
2025-05-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Athletic Performance, Nasal Obstruction, Septoplasty Surgeries

Keywords

nasal surgery, aerobic performance, exercise economy, respiratory work

Brief summary

This retrospective study aims to evaluate the effect of surgical correction of nasal obstruction on aerobic performance parameters in male athletes aged 20-32 years. The main questions it aims to answer are: * Does nasal obstruction surgery impact running economy and ventilation during exercise? * Does it affect oxygen consumption during submaximal running efforts? Researchers will retrospectively compare male athletes who underwent nasal obstruction surgery (experimental group) to matched athletes without nasal obstruction (control group) to assess changes in respiratory function and exercise performance. Participants were assessed by: * Acoustic rhinometry to measure nasal cavity dimensions. * The Nasal Obstruction Symptom Evaluation (NOSE) scale and Epworth Sleepiness Scale (ESS) to evaluate nasal obstruction symptoms and daytime sleepiness. * Incremental treadmill exercise tests to collect data on gas exchange, oxygen consumption, ventilation, and running economy before and after the surgical intervention (or across a similar time period for the control group).

Interventions

PROCEDURESurgical correction of nasal obstruction

Surgical intervention to correct anatomical nasal obstruction, specifically septal deviation, performed under general anesthesia. The procedure involved the repositioning and reshaping of the deviated nasal septum to improve nasal airflow. The surgery was conducted by an otolaryngologist with experience in nasal airway procedures. No additional medications or postoperative interventions beyond standard care (e.g., saline irrigation, analgesics) were administered. Postoperative assessments occurred 2-3 months after surgery, including evaluations of nasal patency, sleep quality, and aerobic performance using treadmill-based gas exchange measurements.

Sponsors

Akdeniz University, Scientific Research Projects Coordination Unit
CollaboratorUNKNOWN
Tuba Melekoğlu
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Masking description

This study was conducted without masking. Participants and investigators were aware of group assignments due to the nature of the intervention (surgical septoplasty). Outcome assessments (aerobic performance tests and symptom questionnaires) were conducted using objective measures and standardized procedures to minimize bias.

Intervention model description

Participants were assigned to one of two parallel groups: an experimental group consisting of athletes with nasal obstruction undergoing septoplasty, and a control group of matched athletes without nasal obstruction who did not receive any intervention. Both groups underwent the same aerobic performance evaluations at baseline and at follow-up (2-3 months).

Eligibility

Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes

Inclusion criteria

For Experimental Group (EG): * Diagnosed with nasal obstruction due to septal deviation and/or inferior turbinate hypertrophy * Experiencing nasal breathing difficulties and sleep disturbance * Deemed eligible for septoplasty and/or inferior turbinoplasty following physical and endoscopic examination * Voluntarily agreed to participate in the study * For Control Group (CG): * No reported nasal obstruction or breathing complications * Matched with EG participants by age, sport discipline, training level, and VO₂max (with a maximum variation of ±5%) * Willing to follow a similar training program to their matched EG counterparts between pre- and post-testing periods

Exclusion criteria

* History of nasal surgery * Presence of cardiopulmonary diseases * Musculoskeletal disorders affecting physical performance or exercise testing * Inability or unwillingness to follow the pre- and post-test training schedule * Any surgical complication that would interfere with post-operative participation in physical testing (note: none occurred in this study)

Design outcomes

Primary

MeasureTime frameDescription
Change in Running Economy (ml/kg/min)Baseline and 2-3 months post-surgeryRunning economy was assessed via an incremental treadmill test by measuring steady-state oxygen consumption (VO₂) at submaximal running speeds (e.g., 8, 10, 12 km/h). Improvement in running economy is defined by a decrease in VO₂ at the same speed, indicating greater efficiency.

Secondary

MeasureTime frameDescription
Change in Oxygen Consumption (VO₂ max and submax VO₂)Baseline and 2-3 months post-surgeryPeak and submaximal oxygen consumption were evaluated using gas exchange analysis during a graded treadmill test. Reduced submaximal VO₂ values are indicative of improved aerobic performance.
Change in VentilationBaseline and 2-3 months post-surgeryVentilatory volume was measured during each stage of the treadmill test. Increases in ventilation at submaximal intensities suggest improved airway function and respiratory efficiency.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026