Postoperative Pain
Conditions
Keywords
Serum calcium levels, Postoperative pain, Ionized calcium levels
Brief summary
This is a prospective observational study. To investigate the effect of serum calcium levels on postoperative pain in patients undergoing abdominal surgery, and to determine whether changes in serum calcium levels are a risk factor for postoperative pain.
Detailed description
This study aimed to measure the total serum calcium and ionized calcium levels both before and after surgery. Additionally, NRS scores were recorded at different time points.
Interventions
DIAGNOSTIC_TESTPeripheral venous blood
Peripheral venous blood was collected before and after the surgery to measure the total serum calcium levels.
DIAGNOSTIC_TESTArterial blood
Arterial blood was collected before anesthesia induction and after removal of the artificial airway to measure ionized calcium levels.
Sponsors
The Second Affiliated Hospital of Chongqing Medical University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
* Aged 18-70 years old * American Society of Anesthesiologists Classification I-III * Patients undergoing elective abdominal surgery under general anesthesia * Patients participate voluntarily and sign an informed consent form
Exclusion criteria
* Patients with a history of severe disease * Patients with chronic preoperative pain and/or long-term analgesic use * Patients with hearing disorders or verbal communication difficulties * Patients with psychiatric disorders or cognitive dysfunction * Patients requiring mechanical ventilation or ICU admission after surgery * Patients with a history of substance or alcohol abuse Patients who could not cooperate with the study for any reason
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The incidence of pain NRS score ≥6 within 48 hours after surgery | From the end of the surgery to 48 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The maximum incisional pain score at 0-12h postoperatively | From the end of the surgery to 12 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| The maximum incisional pain score at 12-24h postoperatively | From 12hours to 24 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| The maximum incisional pain score at 24-48h postoperatively | From 24 hours to 48 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| The maximum visceral pain score at 0-12h postoperatively | From the end of the surgery to 12 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| The maximum visceral pain score at 12-24h postoperatively | From 12 hours to 24 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| The maximum visceral pain score at 24-48h postoperatively | From 24 hours to 48 hours after surgery | NRS score: pain was assessed using a 10-point NRS (range: 0-10, 0 and 10 indicate no pain and the most extreme pain imaginable, respectively） |
| Whether additional analgesia was administered within 48 hours after surgery | From the end of the surgery to 48 hours after surgery | The proportion of patients who received additional analgesia out of the total patient group |
| Patient-controlled intravenous analgesia opioid consumption | From the end of the surgery to 24 hours and 48 hours after surgery | PCIA opioid consumption was assessed by checking the PCIA electronic system |
Countries
China
Contacts
Primary ContactGuangyou Duan, PhD
Outcome results
None listed