Hepatectomy, Intertransverse Process Block, Quality of Recovery (QoR-15)
Conditions
Brief summary
The study aims to assess the analgesic efficacy of the ITPB at the retro-SCTL space in patients undergoing major open hepatectomy surgery. This is assessed by: Primary Objective: Primary outcome measure: ● Assessing the quality of recovery 15 (QoR15) score at 24 and 48 hours Secondary outcome measure: * Number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge * Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow. * Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours * Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU) Hypothesis: The investigators hypothesize that the application of ITPB targeting the retro-SCTL space in patients undergoing open hepatectomy will improve overall quality of recovery and pain score.
Interventions
PROCEDUREIntertransverse process block
The patient(s) will receive a pre-induction Intertransverse process block as pilot study
Sponsors
Chinese University of Hong Kong
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
\- Adult patients aged 18-75 years of ASA I - III physical status classification undergoing open hepatectomy for benign or malignant liver lesion.
Exclusion criteria
* Patient refusal * Patients who are unable to comprehend the QoR15 form * Local or systemic infection * Coagulopathy leading to absolute contraindication to regional anesthesia * Contraindication to local anaesthetics (LA) such as LA allergy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Quality of Recovery (QOR-15) | 24 and 48 hours | The QoR-15 scale is a global measure of postoperative recovery, with a score ranging from 0 (extremely poor QoR) to 150 (excellent QoR). The QoR-15 has since become the most widely reported measure of patient-assessed QoR after surgery. QoR-15 has no units. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Dermatomal blockade on Thorax 30 minutes upon block completion | Up to 30 minutes after block completion | To assess the number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge. This will be done by ice block test. The blockade is considered positive if patient has a reduction in cold sensation over the tested dermatome compared to non-blocked areas such as forehead. |
| 24 hours area under curve of postoperative pain score | Up to 24 hours | Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow. |
| Morphine consumption at 24 and 48 hours postoperatively | At 24 and 48 hours postoperatively | Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours |
| Time to discharge from HDU / ICU | Up to 5 days | Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU) up to 5 days |
Contacts
Primary ContactWing Sum Li, MBChB, BA
Outcome results
None listed