Healthy Skin
Conditions
Brief summary
The aim of this study is to investigate the cleansing effect of one cosmetic product containing Mitopure against a particular matter model pollutant in comparison to an untreated control.
Interventions
OTHERTopical cosmetic cleanser
After applying the model pollutant, the test area will be topically cleaned with the active cosmetic cleanser with Mitopure.
OTHERTopical tap water
After applying the model pollutant, the test area will be topically cleaned with tap water (control).
Sponsors
SGS proderm GmbH
Amazentis SA
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
Two test areas will be defined on both forearms. Area 1 will be located on the right forearm; Area 2 will be located on the left forearm. Treatments will be randomly and balanced assigned to the test areas.
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
Yes
Inclusion criteria
* Written informed consent to participate in the study * Willingness to actively participate in the study and to come to the scheduled visits * Female and/or male * From 18 to 70 years of age * Healthy skin in the test area * Skin type on Fitzpatrick scale: I, II or III
Exclusion criteria
* Female subjects: Pregnancy or lactation * Drug addicts, alcoholics * AIDS, HIV-positive or infectious hepatitis * Conditions which exclude a participation or might influence the test reaction/evaluation * Participation or being in the waiting period after participation in cosmetic and/or pharmaceutical studies pertaining to the test area * Cancer not being diagnosed as cured and requiring chemotherapy, irradiation and/or hormonal treatment within the last 2 years * Active skin disease at the test area * Wounds, moles, tattoos, scars, irritated skin, excessive hair growth, etc. at the test area that could influence the investigation * Any topical medication at the test area within the last 4 weeks prior to the start of the study and during the study * Documented allergies to cosmetic products and/or ingredients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Luminosity (L) | Before pollutant application (t0), immediately after evaporation of the applied pollutant (t1), and 20 minutes after product rinse-off (t2) | Luminosity in test area assessed by HiRIS (High Resolution Imaging System) image analysis will be used to quantify cleaning efficacy. |
Countries
Germany
Outcome results
None listed