Migraine, Patent Foramen Ovale
Conditions
Brief summary
To establish a headache center in China that combines clinical, imaging and laboratory examinations, explore the feasible treatment options for migraine combined with patent foramen ovale, and search for the possible influencing factors, construct models that influence prognosis.
Interventions
DRUGConservative treatment
Receive no antipaletet drug treatment and surgery
DRUGAntipaletet drug
Use of antipaletet drugs.
PROCEDUREPatent Foramen Ovale Closure
Receive the surgery of Patent Foramen Ovale
Sponsors
Peking University Third Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Meet the diagnostic criteria for migraine in the International Classification of Headache (ICHD-3); * Confirmation of patent foramen ovale through transthoracic echocardiography(TTE) or transesophageal echocardiography(TEE)/right heart contrast echocardiography * Agree to participate in the study and sign the informed consent form.
Exclusion criteria
* Can not sign the informed consent form or cooperate with follow-up.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The changes of migraine attacks | 3 months, 6 months, 1 year, 2 years and 3 years | Migraine attacks are an important indicator of improvement in symptoms. The comparison measures included headache frequency, duration, pain degree, VAS scores, HIT-6 scores, HAMA, HAMD, and PSQI. |
Countries
China
Contacts
Primary ContactYu Fu
Outcome results
None listed