Long COVID, Long COVID-19 Syndrome, Long COVID Syndrome
Conditions
Keywords
telerehabilitation
Brief summary
The goal of this study pilot randomized controlled study is to evaluate the feasibility of the study procedures and to compare the preliminary efficacy of a rehabilitation program given in a remote (telerehabilitation) or face-to-face model for adult patients who had confirmed SARS-CoV-2 infection and still have symptoms after eight weeks of infection. The main question it aims to answer is: * Are the study procedures feasible? * Will the two groups have similar results for the preliminary efficacy outcomes? Researchers will compare group telerehabilitation to a face-to-face group to see if it's comparable. Participants will: * Take part in a 60-minute training session, 3 times a week in person or remotely * Visit the clinic before starting the training program and after 8 weeks of training * Keep a diary of their symptoms, if any
Interventions
OTHERRehabilitation program
* 5-minute warm-up including easy global exercises * 5 resistance training exercises targeting upper and lower muscle groups * 30 secondes break between sets * Cooldown with breathing and stretching exercises
Sponsors
Centre intégré universitaire de santé et de services sociaux de la Mauricie-et-du-Centre-du-Québec
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* adult patients (≥18 years) * confirmed SARS-CoV-2 infection defined by positive polymerase chain reaction (PCR) testing and/or antigen test results * referred to the pneumology clinic for a modified British Medical Research Council (mMRC) dyspnea score of 2-3 after a minimum of eight weeks of infection * VO₂max of less than 80% of the predicted value * receiving a medical prescription for rehabilitation following initial assessment by a pulmonologist * being able to walk independently * providing informed consent * having a good internet connection (i.e., a minimum download speed of 4 Mbps and an upload speed of 4 Mbps) * being in possession of a computer or tablet equipped with a camera enabling videoconferencing.
Exclusion criteria
* requiring in-hospital rehabilitation at discharge * evidence of medical instability (i.e., moderate or severe cardiac disease, ischemic or severe hemorrhagic stroke, or neurodegenerative disease, unstable fracture) * history of severe cognitive or mental impairment * already enrolled in another rehabilitation program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The feasibility of study procedures | 8 weeks | This will be evaluated by % of participants that accept to participate in the study (recruitment rate), % of participants who drop out or withdraw from a study (attrition rate), % completed session (adherence rate); number of adverse events and % of participants satisfaction. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Walking capacity | 8 weeks | 6-minute walk test Total distance walked in meters |
| Lower-limb endurance | 8 weeks | 1-minute sit-to-stand test The number of completed sit-to-stand repetitions is record. |
| Physical performance | 8 weeks | Short Physical Performance Battery test Is made up of a set of three tests: standing static balance in three positions (score 0-4); lower limb strength and power through getting up and sitting on a chair(score 0-4); and walking speed at normal pace (score 0-4). And an overall score on 12. |
| Exercise capacity | 8 weeks | Pedaling time on a cycle ergometer at constant load (i.e., 60% of maximum load). |
| Change in Clinical Frailty | 8 weeks | Clinical Frailty Scale (CFS) Frailty score ranging from 1 (very fit) to 9 (terminally ill) |
| Change in Quality of life | 8 weeks | Saint George's Hospital Respiratory Questionnaire (SGHRQ). Scores ranging from 0 to 100 are calculated for each component, as well as a total score that summarizes the responses to all items. A zero score indicates no impairment of quality of life, and higher scores indicate more limitations. |
| Change in Independence in activities of daily living | 8 weeks | The Barthel Index Ten items are scored with a number of points (the scoring is as follows: 0 = unable, 1 = needs assistance/help, 2 = independent), and then a final score is calculated by summing the points awarded to each functional skill. The higher the score, the more independent the patient is. |
Countries
Canada
Outcome results
None listed