Hypoxic Ischemic Encephalopathy of Newborn
Conditions
Brief summary
Hypoxic-ischemic encephalopathy (HIE) is a dangerous illness that happens when a newborn's brain does not receive adequate oxygen and blood flow, which can result in serious effects such as cerebral palsy and epilepsy. Infant diagnosed with HIE required ventilator support and subsequently developed pneumonia. They experienced respiratory problems and feeding challenges. Chest Physical Therapy is the best modalities to clear chest and improve ventilation.
Detailed description
The purpose of this study to investigate the effect of chest physical therapy on Arterial Blood Gases for neonates post hypoxic ischemic encephalopathy (HIE) in Neonatal intensive care unit. Methods: Fifty neonates from both sexes, age from birth to 10 days, post HIE with chest problems were selected from neonatal intensive care unit (NICU) at Minia University hospital, Egypt. They were divided into two equal groups, control group (CG) received traditional medical treatment according to American Academy of Pediatrics (AAP) recommendations and study group (SG) received traditional medical treatment plus Chest Physical Therapy (CPT) modalities in the form of postural drainage, percussion and vibration. The sessions will apply once daily for 6 days/week, each session is about 30 minutes, according to the neonate tolerance till complete clinical cure and discharge from NICU. the outcome will measure by Timing of Arterial blood gases improvement, Duration required for clinical improvement, Duration of Mechanical ventilation, Duration of Hospitalization.
Interventions
OTHERChest Physical Therapy (CPT) modalities , Medical Treatment
Chest Physical Therapy (CPT) modalities in the form of postural drainage, percussion and vibration.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
1 Days to 10 Days
Healthy volunteers
No
Inclusion criteria
* Neonates with chest problems post Hypoxic-ischemic encephalopathy
Exclusion criteria
* Neonates with chest problems due to other Causes except post Hypoxic-ischemic encephalopathy. * unstable medical status * Neonates with Post-operative s' respiratory problems due to any reasons.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Timing of Arterial blood gases improvement | 3-14 days | Time needed to improve Arterial blood gases due to CPT |
| Timing required for clinical improvement | 3-14 days | Time needed to improve clinical signs due to CPT |
| Timing needed for Mechanical Ventilation | 3-7 days | Time needed to Mechanical Ventilation support. |
| Hospitalization time | 5-21 days | All staying duration need for the neonates from admission till discharge from the hospital. |
Contacts
Primary ContactElsayed Mehrem, Associate Professor
Outcome results
None listed