Osteoporosis
Conditions
Brief summary
This study will evaluate the effects of consuming dairy milk versus two plant-based beverages (pea-based, and almond-based) after resistance training sessions (3 times per week for 12 months) on bone properties (bone mineral density, bone geometry), body composition, strength, and functional performance in post-menopausal women and men 50y and older.
Detailed description
The purpose of the study is to compare consumption of dairy milk (1% chocolate milk) to plant-based beverages (protein-matched pea beverage and low-protein almond beverage) after resistance-training sessions on bone mineral density, bone geometric properties, lean tissue and fat mass, muscular strength, and functional performance. One-hundred and fifty postmenopausal women and men 50y or older will be randomized to one of three groups: 1) Dairy milk; 2) pea-beverage; 3) almond beverage. The study will be double-blind, accomplished by chocolate flavoring of each beverage. Participants will do supervised strength-training sessions three times per week for 12 months. After each strength-training session, participants will consume 375 ml of their beverage and then consume 375 ml of their beverage again one hour later.
Interventions
DIETARY_SUPPLEMENTNutritional supplementation during a 12 month resistance training program
1% chocolate milk
Sponsors
University of Saskatchewan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Women need to be postmenopausal (no age limit) * Men need to be 50y or older
Exclusion criteria
* Taking medications that might affect bone * Conditions that might preclude participating in a resistance-training program (determined by the "Get Active Questionnaire"). * Planning 6 weeks of travel during the 12 month intervention period * Planning major surgery during the 12 month intervention period * Already strength training greater than 2 days per week for 30 minutes or longer per session * Allergies to ingredients in the beverages
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in section modulus at the hip (cm to the power of 3) | 12 months | Section modulus measured by dual energy X-ray absorptiometry |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change in knee extension strength (kg) | 6 and 12 months | Knee extension strength determined from 1-repetition maxium |
| Change in lean tissue mass (kg) | 12 months | Lean tissue mass measured by dual energy X-ray absorptiometry |
| Change in lumbar spine bone mineral density (g/cm-squared) | 12 months | Lumbar spine bone mineral density measured by dual energy X-ray absorptiometry |
| Change in hip bone mineral density (g/cm-squared) | 12 months | Hip bone mineral density measured by dual energy X-ray absorptiometry |
| Change in cross-sectional area at the hip (cm-squared) | 12 months | Cross-sectional area measured by dual energy X-ray absorptiometry |
| Change in cortical thickness at the hip (cm) | 12 months | Cortical thickness measured by dual energy X-ray absorptiometry |
| Change in buckling ratio at the hip (no units) | 12 months | Buckling ratio measured by dual energy X-ray absorptiometry |
| Change in bench press strength (kg) | 6 and 12 months | Bench press strength determine from 1-repetition maximum |
| change in 30 second sit to stand (number of repetitions) | 6 and 12 months | Maximal number of times sitting and standing in 30 seconds |
| Change in walking speed (m/s) | 6 and 12 months | walking speed measured over 10 m |
| Change in fat mass (kg) | 12 months | Fat mass measured by dual energy X-ray absorptiometry |
| Change in timed up and go performance (s) | 6 and 12 months | Time for standing from a chair, walking 6 meters and sitting back down |
Countries
Canada
Contacts
CONTACTPhilip Chilibeck, PhD
Outcome results
None listed