Comparison of Anterior Chamber Depth in High Myopes

Comparison of Anterior Chamber Depth Measured by Anterior Segment Optical Coherence Tomography , Ultrasound and Pentacam in High Myopes

Status

Not yet recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06946043

Enrollment

Registered

2025-04-27

Start date

2025-09-30

Completion date

2026-10-30

Last updated

2025-04-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Chamber Depth

Keywords

anterior chamber depth, high myopes

Brief summary

This study aims to compare the accuracy and reliability of anterior chamber depth (ACD) measurements obtained using three imaging modalities: anterior segment optical coherence tomography (A-S OCT), ultrasound biomicroscopy (UBM), and the Pentacam Scheimpflug imaging system. The research focuses on high myopic patients and evaluates the consistency and correlation of these measurements with the degree of myopia.

Detailed description

The research is a cross-sectional, prospective, observational cohort study conducted in ophthalmological settings at Assiut University Hospital, Elforsan Center, and Tyba Center. It investigates the anterior chamber depth (ACD) in high myopes using three advanced diagnostic imaging tools: Anterior Segment Optical Coherence Tomography (A-S OCT): A non-invasive imaging technique for high-resolution cross-sectional imaging of the anterior segment. Ultrasound Biomicroscopy (UBM): An imaging method that uses high-frequency ultrasound to visualize anterior segment structures. Pentacam HR (Scheimpflug Imaging System): A device that provides three-dimensional imaging of the anterior chamber. The primary objective is to determine the mean differences in ACD measurements among these devices. Secondary objectives include assessing the correlation between ACD measurements and the degree of myopia, as well as evaluating the repeatability of measurements for each device.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Patients aged 18 years or older * High myopes with axial length \>26mm or , and refractive error \> -6 ,00 D * Ability to fixate for OCT and Pentacam imaging

Exclusion criteria

* History of ocular surgery or trauma * Presence of corneal pathology * Active ocular inflammation * Inability to fixate for imaging procedure

Design outcomes

Primary

Measure	Time frame	Description
Mean difference in ACD measurements between A-S OCT, UBM, and Pentacam.	During the procedure	The study will calculate and compare the average differences in anterior chamber depth measurements obtained by each device to assess their accuracy and reliability.

Outcome results