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Assessment of Accuracy and Aesthetics Following Automated Mandibular Defect Reconstruction Using AI

Assessment of Accuracy and Aesthetics Following Automated Mandibular Defect Reconstruction Using Artificial Intelligence: A Case Series Study

Status
Not yet recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06945692
Enrollment
4
Registered
2025-04-25
Start date
2025-05-01
Completion date
2026-05-01
Last updated
2025-04-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mandibular Tumor

Keywords

Artificial intelligence, Patient specific reconstruction plates

Brief summary

The Aim of the study is to evaluate Accuracy of automated mandibular defect reconstruction using Artificial intelligence and assessing impact on aesthetic and occlusion outcomes using patient-specific reconstruction plates.

Detailed description

The digital surgical process often requires an expected mandibular reference model. Currently, the common digital surgery process, is to mirror repair or manually look for other similar mandibles for local data fusion and smoothing processing. A more accurate expected reference model is difficult to achieve, time consuming and difficult to promote in clinical practice. Moreover, rapid routing processing often has poor accuracy. For cumulative bilateral lesions, massive lesions, obvious displacement or lesions cross the middle line, there is still no effective method to predict the expected reference model in clinical practice. The main objective for conducting this study is to propose an improved algorithm to overcome the drawbacks of recent studies using 3D Unet and to test the predictability and clinical value of virtually generated 3d models of defected mandible in real patients.

Interventions

PROCEDUREpatient specific reconstruction plates

Use of patient specific reconstruction plates on the 3-D virtually-generated defect using Artificial Intelligence.

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 55 Years
Healthy volunteers
No

Inclusion criteria

* Patients with mandibular tumors, cysts or any benign disease resulting in mandibular continuity defect. * Age group: from 18 - 55 years old. * No sex predilection. * CTs or CBCTs of only healthy mandibles from an online database and real data.

Exclusion criteria

* Patients with mandibular malignant lesions. * Children age group from 2-17. * CTs Of maxilla. * Elderly patients to be excluded due to the normal physiologic bony change.

Design outcomes

Primary

MeasureTime frameDescription
Accuracy Of the virtually Generated 3D model using AIbaselineThe measuring device is the AI model using the Percentage as a unit
Accuracy of AI generated model clinicallybaselineThe measuring device is by Superimposition of both virtual 3-d generated model and real patient CT post operative using software ( blender ) . ( Structural Similarity Index) (SSIM)

Secondary

MeasureTime frameDescription
Aethetic outcomebaselineThe measuring device is Facial appearance using a 4-point score
OcclusionbaselineThe measuring device is Digital occlusion analysis using T-scan and the unit is percentage

Contacts

Primary ContactSarah Moustafa. Moustafa, MSc.
sarah.elayoutti@dentistry.cu.edu.eg56794540
Backup ContactSarah Moustafa. Moustafa, PHD
waleed.elbeialy@dentistry.cu.edu.eg01006133135

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026