Correlation Study Between the Classification of Arthrogenic Motor Inhibition (AMI) and Clinical Assessment After ACL Rupture

Status

Not yet recruiting

Phases

Unknown

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06945133

Acronym

AMIVAL

Enrollment

Registered

2025-04-25

Start date

2026-10-01

Completion date

2028-04-30

Last updated

2026-08-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ACL - Anterior Cruciate Ligament Rupture

Brief summary

The goal of this interventional study is to measure medial vastus inhibition and associate it with AMI classification in patients with ACL rupture. The main question it aims to answer is: Is there a correlation between AMI classification and clinical assessment after ACL rupture ? Participants will undergo surface EMG and Myotonometry.

Interventions

OTHERClinical testing

Intervention includes : * Surface EMG to measure inhibition of the VM and the rectus femoris (RF) on the injured and non-injured sides during attempts at voluntary contractions of the knee extensor muscles. * Myotonometry to measure the stiffness of the semimembranosus and biceps femoris (long head) on the injured and non-injured sides under resting conditions

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

BASIC_SCIENCE

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

18 Years to 44 Years

Healthy volunteers

Inclusion criteria

* Patient, male or female, aged ≥ 18 years and \< 45 years * Patient with an ACL rupture confirmed by MRI * Patient with an ACL rupture ≤ 30 days old * French speaking patient who does not object to the use of his/her data

Exclusion criteria

* Patient with previous ipsi or contralateral knee injury/surgery * Patient with multi-ligament injury * Pregnant or breastfeeding woman

Design outcomes

Primary

Measure	Time frame	Description
Muscle Surface EMG and AMI correlation	From enrollment to Day 30	Electrical signal amplitude, expressed in mV, is evaluated at the level of the VM. This electrical signal amplitude is correlated with the level of muscle activation. It is measured with a surface EMG, which measures the activation of the VM during a voluntary attempt to contract the knee extensors. The ratio: Amplitude of the electrical signal from the injured side of the VM / Amplitude of the electrical signal from the non-injured side of the VM is used to determine the inhibition of the VM. AMI is assessed using the Sonnery-Cottet classification (Sonnery-Cottet et al, 2022)

Countries

France

Contacts

CONTACTBertrand SONNERY-COTTET, MD,PhD

sonnerycottet@aol.com+33 4 37 53 00 22

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Aug 21, 2026