Oral Cancer
Conditions
Keywords
Maximum interincisal opening, Elastography, Masseter muscle, Elasticity
Brief summary
The study aims to assess the hardness of masticatory muscles in post-surgical oral cancer patients using strain elastography ultrasound, calculating the masseter elasticity index and exploring its association with maximum interincisal mouth opening. Furthermore, the study incorporates exercise training to analyze whether changes in masseter hardness can serve as an objective indicator for predicting the improvement of trismus.
Detailed description
This study aims to evaluate the hardness of masticatory muscles in patients who have undergone surgery for oral cancer, using strain elastography ultrasound. Specifically, the research focuses on measuring the elasticity of the masseter muscle by calculating the masseter elasticity index (MEI) and analyzing its correlation with maximum interincisal mouth opening (MIO). Since trismus, or restricted mouth opening, is a common post-surgical complication affecting oral function and quality of life, understanding the relationship between muscle elasticity and jaw mobility is crucial. Additionally, the study incorporates a structured exercise training program designed to improve jaw function in these patients. By monitoring changes in masseter muscle hardness before and after the intervention, the research aims to determine whether variations in muscle elasticity can serve as an objective indicator for predicting improvements in trismus.
Interventions
DIAGNOSTIC_TESTultrasonographic imaging
masseter muscle elasticity
Sponsors
National Taiwan University Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Newly diagnosed oral cancer patients who are scheduled to receive cancer-related treatments (e.g., oral cancer surgery, radiotherapy, chemotherapy, or chemoradiotherapy). 2. Age between 20 and 65 years.
Exclusion criteria
1. Could not communicate. 2. Had any disorder that could influence movement performance.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Masseter muscle elasticity | Pre-intervention, 8 weeks post-intervention | The masseter elasticity index is calculated as the ratio of the average elasticity of the masseter muscle to that of the isolation-coupling Pad (icPad). |
| Maximum interincisal mouth opening | Pre-intervention, 8 weeks post-intervention | Maximum interincisal mouth opening is measured using a mouth-opening ruler, placed at the edges of the upper and lower central incisors to determine the distance. |
Countries
Taiwan
Contacts
CONTACTYueh-Hsia Chen, PhD
PRINCIPAL_INVESTIGATORYueh-Hsia Chen, PhD
National Taiwan University, College of Medicine
Outcome results
None listed