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Neurocognitive Predictors of Health Risk Behaviors

Neurocognitive Predictors of Health Risk Behaviors

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06941181
Enrollment
117
Registered
2025-04-23
Start date
2014-01-20
Completion date
2029-05-31
Last updated
2026-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Substance Use

Brief summary

This study proposes to extend the ongoing longitudinal study of health risk behaviors and obtain new data from former adolescents (followed previously from ages 13-22; Times 1-8) now from ages 23 to 28 (Times 9-11). The goal of this study is to examine the contribution of developing neurocognitive markers to substance use in young adulthood by following a well-characterized longitudinal sample.

Detailed description

The main questions it aims to answer is: what are the long-term effects of valuation and control decision-making systems on health risk behaviors? Participants will complete online surveys assessing their substance use behaviors and perform neurocognitive tasks related to risk processing and cognitive control across three time points.

Interventions

1. risk-processing: Participants choose between two choices across 72 trials of a forced choice decision-making neurocognitive task (Holt and Laury, 2002). Each trial included a high and low monetary outcome with an associated probability of occurring. Each choice option is shown as a pie with ten slices represented probabilities, in which each piece corresponded to ten percent. 2. cognitive control: A multi-source interference task (MSIT; Bush et al., 2003) is used in which participants are presented with three digits and asked to identify the digit different from the others. In the neutral condition, the target's identity is congruent with its relative position. In the interference condition, the target's identity does not match its relative position. There are a total of 96 neutral trials and 96 interference trials.

Sponsors

Virginia Polytechnic Institute and State University
Lead SponsorOTHER

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

\- Adolescents (now young adults) who participated in the original longitudinal project.

Exclusion criteria

* standard contraindications for magnetic resonance imaging at the study onset * history of seizures/stroke * a head injury with \> 10 min of unconsciousness or neurological sequelae

Design outcomes

Primary

MeasureTime frameDescription
substance use behaviorsApproximately every 18 months, 3 times across 5 yearsFrequency (past year and past month use) of cigarette/tobacco, alcohol, cannabis, and other drug use will be asked.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORJungmeen Kim-Spoon, PhD

Virginia Polytechnic Institute and State University

PRINCIPAL_INVESTIGATORBrooks Casas, PhD

Virginia Polytechnic Institute and State University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 13, 2026