Atrophy, Muscular, Undernutrition
Conditions
Brief summary
The objectives of the present study are: 1) to characterize the energy-protein intake of the elderly during hospitalization; 2) to verify the influence of energy-protein intake during hospitalization on muscular (i.e., cross-sectional area of the rectus femoris and vastus lateralis muscles, muscle strength, functionality and level of independence) and clinical (i.e., length of hospital stay, hospital readmission and mortality) at the time of hospital discharge, 2 and 6 months after hospital discharge and; 3) to verify whether energy-protein intake during hospitalization is a significant predictor of loss of function and muscle mass, length of hospital stay, hospital readmission rate and mortality.
Interventions
None listed
Sponsors
University of Sao Paulo General Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
65 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* both sex; * 65 years and older; * hospital stay less than 48 hours;
Exclusion criteria
* cancer in the last 5 years; * delirium; * cognitive deficit that impossibility the patient to read and sign the informed consent form; * neurological disease; * neurodegenerative muscular disease; * patients receive nutrition via enteral and parenteral routes.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Vastus Lateralis Muscle Cross-sectional Area | From date of admission until the date of medical discharge. Up to 30 days. | Vastus Lateralis Muscle Cross-sectional Area will be assessed through ultrasound |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Muscle function | From date of admission until the date of medical discharge. Up to 30 days. | Muscle function evaluated trough battery of test |
| Functional independence | From date of admission until the date of medical discharge. Up to 30 days. | Functional independence will be assessed using Barthel Index. The scores range from 0 to 100. A score of 100 means the individual is fully independent, while lower scores indicate increasing levels of dependence. |
| Handgrip strength | From date of admission until the date of medical discharge. Up to 30 days. | Strength will be evaluated using handgrip strength test |
| Mortality | From date of admission until the date of medical discharge. Up to 30 days. | Mortality rate in percent |
| Hospital readmission post-medical discharge | 1- and 2- months post-medical discharge | Hospital readmission post-medical discharge will be the number of times that he is admitted in the hospital post-medical discharge. |
| Length of hospital stay | From date of admission until the date of medical discharge. Up to 30 days. | Length of hospital stay will be the time (in days) until medical discharge. |
Countries
Brazil
Contacts
Primary ContactHamilton Roschel, PhD
Outcome results
None listed