Nausea
Conditions
Keywords
nausea relief, acupressure wristbands, glp-1 medication, obesity
Brief summary
Nausea is a common side effect of GLP-1RA medications used for treatment of Type 2 diabetes mellitus and obesity. Current recommendations for nausea relief include the use of dietary changes and prescription anti-emetics. Acupressure wristbands Sea-Band are FDA cleared for nausea relief in other indications such as motion sickness, morning sickness in pregnancy, post-operative nausea, chemotherapy associated nausea. We hypothesized that acupressure wristbands could alleviate nausea in persons taking GLP-1RA.
Detailed description
Nausea is the most commonly reported side effect of the class of drugs collectively known as glucagon like peptide-1 receptor agonists (GLP-1RA). GLP-1RAs are FDA approved to treat Type 2 diabetes mellitus (T2DM) and Obesity. Sea-Band is an FDA-cleared set of drug-free elastic wristbands used for nausea relief in several indications including motion sickness, morning sickness in pregnancy, post-operative nausea, chemotherapy associated nausea in persons ages 3 years old and up. The elastic wristbands have a plastic skin facing knob that apples pressure to an acupressure point called pericardium 6 (P6) located below the crease of the wrist. We hypothesize that Sea-Band can alleviate nausea in persons taking GLP-1RA. Participants on GLP-1RA medication with nausea were offered a set of Acupressure wristbands, and followed for four weeks. Weekly touch points assessed the response to nausea relief of the bands. Eligibility for the study included Adults taking GLP-1RA experiencing nausea.
Interventions
DEVICESeaBand
Drug-free, reusable Acupressure elastic wristbands applied to bilateral wrists for nausea relief
Sponsors
Florencia Ziemke
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
prospective interventional study of four weeks duration evaluating the antiemetic effect of wristbands for nausea related to GLP-1RA medication.
Eligibility
Sex/Gender
ALL
Age
18 Years to 90 Years
Healthy volunteers
No
Inclusion criteria
* Adults taking GLp-1RA with nausea
Exclusion criteria
* Adults on GLP-1RA without nausea * Uncontrolled GERD * Hx of Gastroparesis * Other nausea related conditions such as vertigo * History of chronic use of antiemetic medication for other reasons
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Nausea relief | Nausea relief with use of wristbands for every recorded episode, reviewed weekly, for a total of four weeks | Participants will be asked to apply the wristbands at the onset of nausea, and record each nausea episode using a tracker. Weekly touch points with the study team will review their number of nausea episodes, and if nausea relief was obtained. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to onset of relief | Time to nausea relief with use of wristbands for every recorded episode, reviewed weekly, for a total of four weeks | Participants will be asked to apply the wristbands at the onset of nausea, and record each nausea episode, confirm use of wristbands, and if time to relief was under five minutes using a tracker. Weekly touch points with the study team will review their nausea episodes. If relief was obtained, time to relief will be assessed as under or over five minutes. |
Countries
United States
Outcome results
None listed