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Body Surface Area Prediction Impacts on Ventricular Dilatation Prevalence

The Impact of Different Body Surface Area Prediction Equations on Ventricular Dilatation Prevalence in Youth Soccer Players

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06939205
Enrollment
400
Registered
2025-04-22
Start date
2023-12-01
Completion date
2024-12-31
Last updated
2025-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiomyopathies

Keywords

3-D optical imaging, Body surface area, soccer, transthoracic echocardiography

Brief summary

The goals of this observational study are to investigate the accuracy of different predictive equations for body surface area (BSA) estimation and to evaluate the impact of different BSA normalizations on ventricular dilatation prevalence in youth soccer players. Two convenience samples of young soccer players of both genders will be recruited. Acquisition of optical images (for the players of the first sample), two-dimensional echocardiographic assessment (for the players of the second sample), and weight and height measurements (for the players of both samples) will be performed. BSA estimates will be derived from optical images (for the players of the first sample) and from ten different predictive equations obtained from the literature (for the players of both samples). Comparisons between optical imaging - derived BSA and BSA estimates obtained with the ten predictive equations will be performed for the players of the first sample. Absolute and relative values of different echocardiographic variables will be considered for the players of the second sample to assess the ventricular dilatation prevalence.

Interventions

DIAGNOSTIC_TESTAssessment of body surface area and assessment ventricular dilatation prevalence

Estimation of body surface area and quantification of absolute and relative values of echocardiographic variables

Sponsors

University of Turin, Italy
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
12 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* healthy subjects * regular sports participation

Exclusion criteria

\- athletic heart syndrome

Design outcomes

Primary

MeasureTime frameDescription
Body surface area (BSA)Baseline (preseason investigation)Estimation of the BSA value: weight (unit of measurement: kg) and height (unit of measurement: m) will be combined to report BSA in m\^2
Left ventricular dilatation prevalenceBaseline (preseason investigation)Absolute and relative (normalized to body surface area - BSA) values of the following echocardiographic variables will be considered: 1\) left ventricular end-diastolic diameter (LVEDD: absolute value in mm; relative value in mm/m\^2); 2) left ventricular end diastolic volume (LVEDV: absolute value in ml; relative value in ml/m\^2). The left ventricular dilatation will be identified if one or both the relative variables are above the following cut-points: i) LVEDD: 30 mm/m\^2 for males and 31 mm/m\^2 for females; ii) LVEDV: 74 ml/m\^2 for males and 61 ml/m\^2 for females.
Right ventricular dilatation prevalenceBaseline (preseason investigation)Absolute and relative (normalized to body surface area - BSA) values of the fright ventricular basal diameter (RVBD: absolute value in mm; relative value in mm/m\^2) will be considered. The right ventricular dilatation will be identified if RVBD is above the cut-point of 22 mm/m\^2 for both males and females

Countries

Italy

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026