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Urinary Incontinence After Endoscopic Prostatectomy

Predictors of Urinary Incontinence After Endoscopic Transurethral Bipolar Prostatectomy: a Prospective Cohort Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06939140
Enrollment
133
Registered
2025-04-22
Start date
2022-07-01
Completion date
2025-07-01
Last updated
2025-07-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Urinary Incontinence (UI)

Keywords

Stress Urinary Incontinence (SUI), Urge Urinary Incontinence (UUI), Benign Prostatic Hyperplasia (BPH), Bipolar enucleation of the Prostate (BipolEP), Bipolar transurethral reaction of the prostate (B-TURP)

Brief summary

This is a prospective cohort study aiming to identify the preoperative and intraoperative predictors of urinary incontinence after endoscopic transurethral bipolar prostatectomy

Detailed description

Benign prostatic hyperplasia (BPH) represents a progressive, age-related proliferation of prostatic stromal and epithelial cells, with histopathological changes typically manifesting after the fourth decade of life. Epidemiological studies demonstrate a prevalence increasing from approximately 50% in men aged 60 years to 90% by age 85 years. The condition frequently results in bladder outlet obstruction, clinically presenting as lower urinary tract symptoms (LUTS) that are conventionally categorized into obstructive (voiding) and storage (irritative) subtypes. Among contemporary surgical interventions, transurethral bipolar prostatectomy techniques - including bipolar transurethral resection of the prostate (B-TURP) and bipolar laser enucleation of the prostate (BipoLEP) - have established efficacy in the management of BPH-induced LUTS, as demonstrated in randomized controlled trials and meta-analyses. Postoperative urinary incontinence (UI) remains among the most clinically significant complications following surgical management of benign prostatic hyperplasia (BPH). Early transient UI represents a frequently observed postoperative sequela, serving as both a primary source of patient anxiety regarding surgical intervention and a substantial determinant of postoperative dissatisfaction. While the majority of transient UI cases demonstrate spontaneous resolution within 1-6 months postoperatively, persistent UI develops in a clinically relevant subset of patients. This chronic manifestation constitutes a serious long-term complication which decrease the quality of life of the patients. Reported rates of urinary incontinence following BPH surgery exhibit considerable variability, which may be attributed to differences in surgical techniques, inconsistent definitions of incontinence, and heterogeneity in assessment methods. Moreover, the majority of studies fail to specify the type or duration of incontinence. Predictors of postoperative urinary incontinence (UI) following endoscopic surgery for BPH require systematic evaluation to optimize preoperative counseling and identify high-risk patients. A thorough discussion of UI risk should be incorporated into the shared decision-making process. This prospective study aims to identify and characterize preoperative and intraoperative risk factors for stress (SUI) and urge (UUI) urinary incontinence in patients undergoing endoscopic BPH surgeries.

Interventions

PROCEDUREBipolar prostatectomy

Endoscopic transurethral bipolar enucleation or reaction of the prostate

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
50 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Males ≥50 years undergoing primary B-TURP/BipolEP for BPH * Preoperative IPSS ≥8, Qmax ≤15 mL/s, prostate volume ≥30mL * No prior incontinence/neurological bladder dysfunction

Exclusion criteria

* Prostate cancer history * Concurrent anti-incontinence procedures

Design outcomes

Primary

MeasureTime frameDescription
Preoperative predictors of urinary incontinenceAt 6 months after the procedureAssociation between patients' preoperative parameters and occurrence of urinary incontinence after the procedure

Secondary

MeasureTime frameDescription
Intraoperative predictors of urinary incontinenceAt 6 months after the procedureAssociation between intraoperative parameters and occurrence of urinary incontinence after the procedure

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026