Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy

Effect of an Enhanced Recovery After Surgery Program on Outcomes After Pancreatoduodenectomy; Experience From Two Referral Centers in Central Greece.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06935448

Enrollment

170

Registered

2025-04-20

Start date

2019-07-01

Completion date

2025-05-30

Last updated

2025-04-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Enhanced Recovery After Surgery, Pancreatectomy, Pancreatic Cancer Resectable

Keywords

pancreatectomy, enhanced recovery after surgery, pancreatic cancer resectable, outcomes research

Brief summary

This study assesses whether patients with pancreatic cancer who undergo surgery experience improved outcomes following the implementation of a multidisciplinary care pathway, specifically an enhanced recovery after surgery (ERAS) program. This pathway includes various interventions in the preoperative, intraoperative, and postoperative care of these patients, all aimed at enhancing their health status and postoperative results.

Detailed description

This prospective observational study is conducted by the same surgical team at two high-volume pancreatic cancer referral centers in Greece. Patients undergoing elective pancreatic surgery are prospectively enrolled and managed according to a standardized ERAS protocol (ERAS group). A control group, which received standard perioperative care before the implementation of ERAS, was retrospectively selected and matched based on demographic and clinical parameters. The primary study endpoint is the length of hospital stay (LOS), while secondary endpoints include 30-day mortality and morbidity.

Interventions

OTHERenhanced recovery after surgery

ERAS group follows the enhanced recovery after surgery program which involves 20 elements

Study design

Observational model

CASE_CONTROL

Time perspective

OTHER

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* adult patients * diagnosis of pancreatic cancer * elective open pancreatic surgery

Exclusion criteria

* age \<18 years * emergency pancreatic surgery * other surgical procedures * missing data * lost to follow-up

Design outcomes

Primary

Measure	Time frame	Description
impact on length of stay	within 30 days of surgery	total number of days spent in the hospital including any readmission

Secondary

Measure	Time frame	Description
impact on overall morbidity	within 30 days from surgery	number of any perioperative adverse events

Countries

Greece

Contacts

Primary ContactDESPOINA LIOTIRI, MD MSc PhD(c)

deppieliotiri@gmail.com00302410996000

Backup ContactATHINA SAMARA, MD MSc PhD(c)

at.samara93@gmail.com

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026