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Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update

Endoprosthetic Replacement for Pathological Fractures of the Hip: A 35-year Update

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06935071
Enrollment
300
Registered
2025-04-18
Start date
2016-08-04
Completion date
2027-08-04
Last updated
2026-09-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Fracture Pathologic, Hip Fractures, Pathological Fracture, Pathological Fracture of Hip

Keywords

hip fractures, pathological hip fractures, hip fracture parthologic, pathological fracture of hip, 16-1122, Memorial Sloan Kettering Cancer Center

Brief summary

This study will be based on a retrospective review of patients who received endoprosthetic reconstruction for pathologic fracture of the proximal femur. The objectives would be two-fold: (1) to compare rates ofambulation, pain, and survival to the historic cohort and (2) to identify predictors of ambulation in the current population.

Interventions

Patient data will be analyzed to ensure that all data fields are available and that suitable sample size is available to answer the research objectives. The rate of ambulation at discharge, ambulation at 3 month follow up (if available), time to death, and pain score between the historic cohort with a current cohort of patients will be compared.

Sponsors

Memorial Sloan Kettering Cancer Center
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Participants have received endoprosthetic reconstruction for pathologic fracture of the proximal femur

Exclusion criteria

* Participants with fractures greater than 3mm from the lesser trochanter * Participants without histopathologic confirmation of tumor

Design outcomes

Primary

MeasureTime frameDescription
Comparison of rates of ambulation, pain, and survival to the historic cohortup to 10 yearsThis study will be based on a retrospective review of patients who received endoprosthetic reconstruction for pathologic fracture of the proximal femur.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATORJohn Healey, MD

Memorial Sloan Kettering Cancer Center

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Sep 5, 2026