Gastric Cancer Patients Undergoing Minimally Invasive Gastrectomy
Conditions
Brief summary
For patients diagnosed with early gastric cancer involving submucosal invasion, super-ESD indications, or lymph node metastasis, a combination of preoperative endoscopic ultrasound and abdominal contrast-enhanced CT was utilized to ascertain the depth of tumor invasion and to identify any suspicious metastatic lymph nodes in the vicinity of the stomach. Subsequently, a local full-thickness resection, coupled with or followed by individualized precise lymph node dissection, was conducted to fulfill the following objectives: ① To investigate the safety, feasibility, and efficacy of local resection for patients meeting super-ESD criteria; ② To offer a clinical foundation for the individualized and precise lymph node dissection treatment of early gastric cancer.
Interventions
PROCEDURESixty patients with early gastric cancer in stage T1bN0-1M0 were divided into Group A-N0 and Group B-N + according to the presence or absence of lymph node metastasis. When the enrolled patients und
Patients in group A-No lymph node metastasis, who underwent simple Double-Endoscopic Combined with local full-thickness resection. Patients in group B-imaging examination showed lymph node metastasis. patients were randomly divided into Group N + a and Group N + b. Group N + a: Local full-thickness gastric wall and lymph nodes dissection on D1 or D1 + were performed with Double-Endoscopic Group N + b: Traditional standard surgical gastrectomy and D1 or D1 + lymph nodes dissection was performed .
Sponsors
Hebei Medical University
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
1. Age 18-70 years old; 2. Endoscopic pathological diagnosis: adenocarcinoma; 3. Enhanced abdominal CT combined with endoscopic ultrasound clinical staging: T1bN0-1M0. 4. Has not received other treatment; 5. No other serious comorbidities; 6. Agree to participate in the study and sign the informed consent form.
Exclusion criteria
1. Pregnant or breastfeeding women 2. History of previous abdominal surgery 3. History of other previous malignancies 4. Can patients with severe heart, lung, brain diseases tolerate surgical treatment
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of recurrence | Within 2 years |
Secondary
| Measure | Time frame |
|---|---|
| The operation time, complications and hospital stay were recorded | 30 days |
Contacts
Primary ContactQun Zhao, Ph.D
Backup ContactGang pei Yang, Master's degree
Outcome results
None listed