Laparoskopic Cholecystectomy, Modified Thoracoabdominal Nerve Block (M-TAPA), Transversus Abdominis Plane (TAP) Block
Conditions
Keywords
remifantanile conception, acute pain, Postoperatif pain
Brief summary
Laparoscopic cholecystectomy is a frequently performed surgical procedure and is considered the gold standard for treating symptomatic gallstone disease. Although laparoscopic cholecystectomy is considered minimally invasive, it can cause moderate to severe pain in the postoperative period. Poorly controlled early postoperative pain can impair recovery quality and increase the risk of postoperative pulmonary complications as a risk factor for chronic pain development. Multimodal analgesia, including opioids, is used to limit pain following laparoscopic cholecystectomy. However, opioid treatment may lead to side effects such as postoperative nausea and vomiting (PONV), respiratory depression, and constipation. Nerve blocks provide better pain control, reduce opioid consumption in the postoperative period, and offer advantages such as fewer side effects and a lower risk of pulmonary and cardiac complications. In our clinic, a multimodal analgesia approach is preferred for patients undergoing laparoscopic cholecystectomy. In addition to intravenous analgesic agents, peripheral nerve blocks are administered based on patient preference (for all eligible and consenting patients). This study aims to compare the postoperative analgesic efficacy of the Transversus Abdominis Plane (TAP) Block and the Modified Thoracoabdominal Nerve Block with a Pericostal Approach (M-TAPA) in patients undergoing laparoscopic cholecystectomy. Standard analgesic methods are applied to patients who do not consent to peripheral nerve block administration.
Interventions
DRUGTransversus Abdominis Plane (TAP) Block
Transversus Abdominis Plane (TAP) Block is performed under ultrasound guidance before the surgical procedure and anesthesia induction, with the patient in the supine position.
DRUGModified Thoracoabdominal Nerve Block (M-TAPA)
Modified Thoracoabdominal Nerve Block (M-TAPA) is performed under ultrasound guidance before the surgical procedure and anesthesia induction, with the patient in the supine position.
Sponsors
Ankara Etlik City Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Caregiver, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
* 18 to 65 years old * American Society of Anesthesiologists (ASA) physical status I-II-III * Body mass index 18 to 30 kg/m2 * Elective laparoscopic cholecystectomy surgery
Exclusion criteria
* Under 18 and over 65 * ASA score IV and above * Advanced co-morbidity * History of bleeding diathesis * Patient refusing the procedure * Chronic opioid or analgesic use * Patients who will operate under emergency conditions * Block injection site infection * Known allergy to local anesthetics * Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pain scores | First 24 hours after surgery | Pain will be assessed at rest and while movement using the from 0 (no pain) to 10 (worst |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Intraoperative remifentanil consumption | During The intraoperatif period | The amount of remifentanil that patients need to maintain anesthesia during the intraoperative period will be recorded |
Countries
Turkey (Türkiye)
Contacts
Primary ContactMÜRÜVVET TAŞKIR TURAN, MD
Backup ContactMUSA ZENGİN, Associate Professor
Outcome results
None listed