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Delta Variation to Guide Hemodynamic Optimization

A NEW APPROACH IN THE MANAGEMENT OF INTRAOPERATIVE ARTERIAL HYPOTENSION BASED ON DELTA VARIATION OF HEMODYNAMIC PARAMETERS: A RANDOMISED CLINICAL TRIAL

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06932484
Acronym
DELTA
Enrollment
104
Registered
2025-04-17
Start date
2025-06-01
Completion date
2027-06-01
Last updated
2025-07-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hemodynamic MAP Stability

Brief summary

intraoperative hemodynamic optimization will be based on the percentage of variation of the parameters

Interventions

PROCEDUREparameters

during surgery hemodynamic will be optimized based on percentage variation of different variables

Sponsors

Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

All patients \> 18 years old scheduled for major abdominal

Exclusion criteria

Body Mass Index \> 35 kg/m2 Pregnancy Refusal to sign written informed consent Urgent and/or emergency surgery

Design outcomes

Primary

MeasureTime frameDescription
time weighted average of mean arterial pressurethe end of surgerywe will avoid hypotensive episodes by using a predictive approach and then calculate the TWA-MAP \< 65 mmHg

Countries

Italy

Contacts

Primary Contactandrea russo, physician
andrea.russo@policlinicogemelli.it+39-06-30153212

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026