Normal Pediatric Liver and Spleen SWE

Normal Liver and Spleen Stiffness Values Using Shear Wave Elastography in Children

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06930066

Acronym

SWE

Enrollment

434

Registered

2025-04-16

Start date

2025-07-30

Completion date

2026-01-30

Last updated

2026-03-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver Stiffness, Normal Organ Elasticity, Pediatric Elastography, Shear Wave Elastography in Healthy Children, Spleen Stiffness

Keywords

Shear Wave Elastography, Liver Stiffness, Spleen Stiffness, Pediatric Elastography, Normal Reference Values, Organ Stiffness Measurement

Brief summary

This observational study aims to determine normal liver and spleen stiffness values in healthy children using shear wave elastography (SWE). The study will include participants from the pediatric age group without known liver or spleen disease. SWE measurements will be performed non-invasively to establish reference values. The results may contribute to improving diagnostic accuracy in pediatric elastography applications.

Detailed description

Shear wave elastography (SWE) is a non-invasive imaging method used to assess tissue stiffness. While reference values for SWE have been established in adults, data regarding normal liver and spleen stiffness in children are limited. This single-center, cross-sectional observational study aims to establish normative SWE values for the liver and spleen in the pediatric age group. Children with no known liver or spleen pathology will undergo standardized SWE measurement under controlled conditions. Age-specific and sex-specific reference ranges will be analyzed, which may contribute to enhancing the clinical utility of SWE in pediatric practice.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Months to 18 Years

Healthy volunteers

Yes

Inclusion criteria

* Healthy children aged 0-18 years * No known liver or spleen pathology * Written informed consent obtained from parents or guardians

Exclusion criteria

* Known liver disease (e.g., hepatitis, cirrhosis) * Known spleen disease (e.g., splenomegaly) * Any history of liver or spleen disease * Age outside the 0-18 years range

Design outcomes

Primary

Measure	Time frame	Description
Normal liver and spleen stiffness values	Day 1	This study aims to establish reference values for liver and spleen stiffness in healthy children using shear wave elastography (SWE).

Countries

Turkey (Türkiye)

Outcome results