Ocular Characteristics in Patients With Craniosynostosis

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06928727

Acronym

COPACA

Enrollment

Registered

2025-04-15

Start date

2025-04-04

Completion date

2026-11-01

Last updated

2026-02-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Amblyopia, Craniosynostosis, Intracranial Hypertension, Strabismus

Keywords

Craniosynostosis, strabismus, amblyopia, intracranial hypertension

Brief summary

Craniosynostosis are cranial deformations due to the premature closure of one or more cranial sutures. These deformations affect approximately one in 2.500 births. In most cases, craniosynostoses are isolated with unknown (non syndrome). On the other hand, 20% of these deformations are associated with other concentration (syndrome). Craniosynostosis has morphological (associated dysmorphism) and functional (growth conflict between the skull and the brain) repercussions. Ophthalmological disorders are frequent: refractive disorders, oculomotor disorders, optic nerve damage, sensory damage. This retrospective study aims to describe the ocular clinical characteristics associated with craniosynostosis in patients followed at the Amiens University Hospital.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Diagnosis of craniostenosis

Exclusion criteria

* Posterior plagiocephalia

Design outcomes

Primary

Measure	Time frame	Description
Rate of strabismus and amblyopia	6 months	Rate of strabismus and amblyopia

Secondary

Measure	Time frame	Description
Rate of intracranial hypertension	6 months	Rate of intracranial hypertension

Countries

France

Contacts

CONTACTTran Thi Ha Chau, Pr

tran.chau@chu-amiens.fr33+322089224

Outcome results