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Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device

Chronic Loose Stools Following Right-sided Hemicolectomy for Colon Cancer and the Association With Bile Acid Malabsorption and Small Intestinal Bacterial Overgrowth Using a Novel Sampling Device

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06927011
Enrollment
20
Registered
2025-04-15
Start date
2025-10-31
Completion date
2028-12-30
Last updated
2026-07-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer

Brief summary

The goal of this clinical research study is to learn about gastrointestinal symptoms in participants who have undergone SC or RC and their impact on the quality of life of these participants.

Detailed description

To estimate the microbiota and bile acid profiles at multiple levels of the small intestine and proximal neo-colon in patients after RC and participants after SC.

Interventions

BEHAVIORALCapscan

Participants will be asked to swallow 2 small devices (called Capscan), which will collect samples of intestinal fluid as they move through participants small intestine and colon. This device is not FDA approved but has been deemed to have no significant risk. The investigator can explain how it is designed to work. Participants will also answer surveys about participants quality of life. Participants in this study will be over after all study procedures are completed.

Sponsors

M.D. Anderson Cancer Center
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to 85 Years

Inclusion criteria

* Both men and women of all races and ethnic groups are eligible for this trial who meet the above criteria.

Exclusion criteria

* Children will not be enrolled in this study. * Pregnant women will not be enrolled in this study. * Cognitively impaired subjects will not be enrolled in this study.

Design outcomes

Primary

MeasureTime frame
Overall Survival (OS)Through study completion; an average of 1 year.

Countries

United States

Contacts

CONTACTAnusha Thomas, MBBS
asthomas1@mdanderson.org(713) 794-1439

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 17, 2026