Acute Renal Failure, Neonatal Morbidity
Conditions
Keywords
Cerebral oximetry, NIRS, Neonate, Ventilated, Kidney injury
Brief summary
Cerebral oximetry monitoring allows clinicians to optimize blood flow to the brain and oxygenation using the SafeBoosC treatment guideline. The guideline's interventions aims to stabilize blood pressure and oxygen levels. As low blood pressure is a risk factor for the development of kidney injury, normalizing blood pressure may decrease the incidence of kidney injury in new-borns who are on ventilator.
Interventions
OTHERIntervention Arm- Cerebral Oximetry + Treatment Guideline
if the cerebral oximeter shows low values, a pre designed treatment guideline will be followed and corrective actions taken.
Sponsors
Rigshospitalet, Denmark
St. John's Research Institute
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
1 Days to 28 Days
Healthy volunteers
No
Inclusion criteria
* \> 28 weeks of gestation Invasively ventilated
Exclusion criteria
* major anomalies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| composite outcome of death and acute kidney injury | From randomization to discharge up to 2months of life | composite outcome of death and acute kidney injury |
Countries
India
Contacts
Primary Contactsaudamini Nesargi, Dr.
Outcome results
None listed