Chronic Disease, Lung Diseases
Conditions
Keywords
Lung Health, Chronic Disease
Brief summary
This project will compare the health effects of public housing renovation, neighborhood built and social environment improvements, and indoor air purification, alone and in combination, as well as the cost effectiveness of each approach. STUDY 1: The study will assess the effects of public housing and neighborhood environment (built and social) improvements on health-related behaviors, psychosocial and physiologic stress, and self-reported and physiological markers of lung health and chronic disease. STUDY 2: The study will determine whether indoor air purification can positively impact lung health in public housing sites not undergoing housing renovation, comparing a site near industrial pollution vs one less contaminated.
Detailed description
Participants will complete surveys, physical exam, lung function tests, and blood draw. An indoor air purifier with a usage tracker and an indoor air quality monitor will be provided, and used filters will be analyzed.
Interventions
OTHERIndoor Air Purification
An indoor air purifier with a dual HEPA/activated carbon filter, a usage tracker, and an indoor air quality monitor will be installed in public housing residences.
OTHERNeighborhood Improvements
Improved built environment (green space, sidewalks, street lights) and social environment (educational and workforce development programs, wrap-around social services, Internet access).
OTHERHousing Improvements
High-quality public housing
Sponsors
University of Alabama at Birmingham
National Institute of Nursing Research (NINR)
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 89 Years
Healthy volunteers
Yes
Inclusion criteria
* Adults age 18 years and older * English speaking * Residents of one of 4 public housing site in Birmingham, Alabama
Exclusion criteria
* Individuals who are not 18 years or older * Do not speak English * Do not meet the residency criteria
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in Patient-Reported Outcomes Measurement Information System (PROMIS-10) Global Health | Baseline, 12 months, 24 months | A self-reported measure of physical, mental, and social health. 10 item questionnaire T-score metric from zero to 100 where higher T-scores indicate better health. |
| Change in Allostatic load | Baseline, 12 months | Measure of cumulative stress burden as the number of 10 indicators above a threshold: (1) serum albumin \<3.8 g/dL, (2) C Reactive Protein (CRP) \>3 mg/L, (3) High-Density Lipoprotein (HDL) \<40 mg/dL, (4) total cholesterol ≥240 mg/dL, (5) heart rate ≥90 beats/min, (6) systolic Blood Pressure (BP) ≥140 mmHg, (7) diastolic BP ≥90 mmHg, (8) serum creatinine ≥1.3 mg/dL, (9) Blood Urea Nitrogen (BUN) ≥18 mg/dL, and (10) waist circumference \>88 cm in women, \>102 cm in men. |
| Change in Indoor Air Quality | Baseline, 6 months, 12 months (Study 2 only) | Particulate matter (PM2.5). Measures particles in the air that are 2.5 micrometers or smaller in diameter. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The percentage change in FEV1/FVC | Baseline, 6 months, 12 months (Study 2 only) | FEV1/FVC. A measure of lung funtion that compares the amount of air exhaled in the first second (FEV1) to the total amount of air exhaled in a forced breath (FVC). |
Countries
United States
Contacts
CONTACTGabriela R Oates, PhD
CONTACTJoy R Ledvina, Program Director, MBA
PRINCIPAL_INVESTIGATORGabriela R Oates, PhD
University of Alabama at Birmingham (UAB)
Outcome results
None listed