Goiter, Nodular, Thyroid Cancer, Total Thyroidectomy
Conditions
Brief summary
This study aims to investigate, based on existing knowledge, the incidence of occult thyroid carcinoma in a cohort of patients with MNG, providing new insights into the prevalence and characteristics of thyroid malignancies in MNG. It seeks to contribute to optimizing diagnostic evaluations for patients with multinodular goiter.
Detailed description
This retrospective study included patients with a preoperative diagnosis of multinodular goiter who underwent total or partial thyroidectomy from January 2018 to May 2024 at the Department of Medical and Surgical Sciences at the University Hospital Ospedali Riuniti in Foggia. The study's objective was to investigate the incidence of thyroid carcinoma in patients undergoing thyroidectomy for MNG, also analyzing associated demographic and clinical variables.
Interventions
PROCEDUREtotal or partial thyroidectomy
Total thyroidectomy is a surgical procedure that involves the complete removal of the thyroid gland. It is performed to treat conditions such as thyroid cancer, large goiters, or severe hyperthyroidism. The surgery is typically conducted under general anesthesia through an incision in the lower neck. Postoperative management may include hormone replacement therapy with levothyroxine to compensate for the loss of thyroid function. Potential complications include hypocalcemia due to parathyroid gland injury and vocal cord dysfunction from recurrent laryngeal nerve damage.
Sponsors
University of Foggia
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* patients diagnosed with multinodular goiter via thyroid ultrasound, with or without FNA cytology. * patients who underwent surgery. * availability of complete clinical data
Exclusion criteria
* history of thyroid carcinoma or other thyroid neoplasms. * not completed postoperative follow up. * patients with preoperative FNA results indicating malignancy (TIR 4-5), suspicion of malignancy (TIR 3), or indeterminate significance (TIR 1)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| incidence of occult thyroid carcinoma | 6 years | Incidence of occult thyroid carcinoma in a cohort of patients with multinodular goiter, providing new insights into the prevalence and characteristics of thyroid malignancies. |
Countries
Italy
Outcome results
None listed