Alloknesie, Atopic Dermatosis
Conditions
Brief summary
Alloknesia is defined as pruritus (= itching) triggered by light mechanical stimuli, which are responsible for the perception of light touch under physiological conditions, but which are perceived as pruritic under pathological conditions. Alloknesia occurs mainly in the context of chronic pruritus. Consequently, patients suffering from chronic pruritus frequently perceive light touch sensations as pruritic, which can be particularly unpleasant and alter human interactions and quality of life on a daily basis. However, the epidemiology and burden of alloknesia have never been studied, whatever the cause of chronic pruritus.Atopic dermatitis is one of the main diseases causing chronic itching, and patients frequently complain of alloknesia. In this study, the investigators are studying the frequency of alloknesia in patients with atopic dermatitis and measuring the consequences of alloknesia in these patients.
Interventions
None listed
Sponsors
University Hospital, Brest
Almirall, S.A.
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years * No opposition from the patient * Diagnosis of atopic dermatitis more than 6 months old
Exclusion criteria
* Patients who are physically or mentally unable to complete the questionnaires. * Patients on systemic treatment for 1 month or more * Refusal to participate * Patients under legal protection (guardianship, curatorship) * Patients under court protection
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alloknesia diagnostic questionnaire | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | The questionnaire consists of a single question: 'Can the touch of your skin by clothing, air movements or the light touch of an object or another person trigger itching? |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| WI-NRS scale / Worst Itch Numeric Rating Scale | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | Digital pruritus scale, measuring the worst daily itching intensity 0 to 10. 0: no itching 10: worst itch imaginable |
| ItchyQoL questionnaire / quality-of life instrument for pruritus | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | Quality-of life instrument for pruritus Itch-related quality of life 0 to 110 |
| DLQI questionnaire / Dermatology Life Quality Index | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | Skin-related quality of life 0 to 30 |
| HADS questionnaire / Hospital Anxiety and Depression Scale | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | The HAD scale is an instrument for screening for anxiety and depressive disorders. 0 to 21 |
| PUSH-D questionnaire / Patient Unique Stigmatization Holistic tool in dermatology | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | PUSH-D allows a comprehensive view of the degree of stigmatization in visible skin disorders. 0 to 68 |
| Stress perçu : PSS / Perceived Stress Scale | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | The PSS (Perceived Stress Scale) is a scale for measuring perceived stress. 0 to 40 |
| Epworth questionnaire / sleepiness scale | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | The Epworth Test is a self-administered questionnaire that assesses subjective sleepiness and fatigue. 0 to 21 |
| ISS questionnaire / Sexual Satisfaction Index | At enrollment. If the patient completes the questionnaires at home, they will be brought back by the patient at their next medical consultation. | Satisfaction with sexual relations 25 to 175 |
Countries
France
Contacts
CONTACTLaurent MISERY, PUPH
Outcome results
None listed