Clinical and Radiographic Success of Pulpotomy Using Neoputty Mineral Trioxide Aggregate Versus Pulpectomy Using Endoflas In Primary Molars With Irreversible Pulpitis: A Randomized Controlled Trial

Status

Not yet recruiting

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06922578

Enrollment

Registered

2025-04-10

Start date

2025-05-01

Completion date

2026-06-01

Last updated

2025-04-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulpitis - Irreversible

Brief summary

The goal of this randomized clinical trial is to evaluate the clinical and radiographic success of pulpotomy using Neoputty MTA vital primary molars diagnosed with symptomatic irreversible pulpitis. The main question it aims to answer is: Will Neoputty MTA pulpotomy have higher clinical and radiographic success in comparison to Endoflas pulpectomy in primary molars with irreversible pulpitis?

Interventions

PROCEDURENeoPUTTY MTA pulpotomy

Neoputty MTA pulpotomy performed in vital primary molars with symptomatic irreversible pulpitis

PROCEDUREEndoflas pulpectomy

Endoflas pulpectomy in vital primary molars with symptomatic irreversible pulpitis

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Age

4 Years to 9 Years

Healthy volunteers

Yes

Inclusion criteria

* Children with spontaneous pain lasting a few seconds to several hours. * Pain is intensified by thermal stimulus and persists after its removal. * Pulp hemorrhage after performing access cavity and deroofing of pulp chamber showing reddish pink healthy pulp tissue. * Radicular pulp health is verified by achieving hemostasis within six minutes of compression using a cotton pellet with 2% sodium hypochlorite. * Absence of peri-apical or inter-radicular radiolucency, widening of periodontal ligament space, internal or external root resorption.

Exclusion criteria

* Unrestorable primary molars. * Primary molars with uncontrolled pulp hemorrhage or pulp necrosis. * Medically compromised patients who have systemic disease. * Uncooperative children who refuse treatment.

Design outcomes

Primary

Measure	Time frame	Description
postoperative pain	within 24 hours, after 1 week, 3, 6, 9, and 12 months	postoperative pain will be assessed using the visual analogue scale (VAS) within 24 hours, after 1 week, 3, 6, 9, and 12 months. The patients are asked to point to the face that best represents how they are feeling at the follow-up visits.

Contacts

Primary Contactmanar motawie el nimr, masters

manar.motawie@dentistry.cu.edu.eg0201101778899

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026