Examination of the Large Intestine With Camera Capsule in Patients With Blood Stream Infection With Gut-associated Bacteria

Colonic Capsule Endoscopy for Screening of Neoplasms in Patients With Anaerobic Bacteremia

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06919068

Acronym

AB-care

Enrollment

100

Registered

2025-04-09

Start date

2025-04-23

Completion date

2027-12-31

Last updated

2025-11-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal Cancer (CRC), Colorectal Cancer and Pre-cancer Polyps, Blood Stream Infection, Anaerobic Infection, Bacteriaemia

Keywords

Colorectal Cancer, Anaerobic bacteria, Bacteria, anaerobic, Cancer, colorectal, Bacteremia, Blood stream infection, Colon capsule endoscopy

Brief summary

The goal of this observational study is to diagnose colorectal cancer or precancerous tumors in participants over the age of 18 hospitalized with blood stream infection with anaerobic gut-associated bacteria. The main question it aims to answer is: • How prevalent is cancer and precancerous tumors in the large intestines and rectum in patients with anaerobic bacteremia? Participants will be offered an examination using colon capsule endoscopy 4-8 weeks after discharge.

Interventions

DIAGNOSTIC_TESTColon capsule endoscopy

PillCam Colon 2

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Yes

Inclusion criteria

* Older than 18 years * Blood culture with growth of one or more of the following bacterial genera Bacteroides, Clostridium, Filifactor, Fusobacterium, Gemella, Granulicatella, Parvimonas, Peptostreptococcus, Prevotella, Solobacterium, Peptoniphilus, Ruminococcus, Finegoldia and Streptococcus. * Able to provide oral and written informed consent * Able to read and speak Danish

Exclusion criteria

* Prior colorectal cancer diagnosis * History of stenosis of the gastrointestinal tract * Previous treatment of inflammatory bowel disease * Previous major surgery of the gastrointesinal tract (e.g. gastric bypass) * Colostomy * Pacemaker/ICD * Pregnancy or breastfeeding * Allergies to the bowel preparation regimen * Severe kidney disease * Focus of infection in skin and soft tissue or outside the truncus (e.g. decubitus, diabetic foot ulcer) * Tumor in the colon or rectum at diagnostic imaging * Transfer to other hospital outside the region

Design outcomes

Primary

Measure	Time frame	Description
Colorectal cancer and precancerous tumors	4-8 weeks after hospitalization with anaerobic gut-associated bacteria	Prevalence of colorectal cancer and precancerous tumors using colon capsule endoscopy

Countries

Denmark

Contacts

Primary ContactCharlotte Nielsen Agergaard, MD

charlotte.agergaard@rsyd.dk004565414797

Backup ContactMark Bremholm Ellebæk, Professor

Mark.Ellebaek1@rsyd.dk004540880511

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026