Analysis of Intramedullary Nail and Prosthetic Reconstruction After Surgical Treatment of Bone Metastases of Proximal Femur

Complications, Implant Survival and Functional Results After Surgical Treatment of Bone Metastases of Proximal Femur With Intramedullary Nail or Prosthetic Reconstruction

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06918860

Enrollment

600

Registered

2025-04-09

Start date

2024-05-30

Completion date

2025-12-31

Last updated

2025-04-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bone Metastases

Keywords

bone metastases, proximal femur

Brief summary

The investigators will collect data of patients treated surgically for impending or pathological fracture of the proximal femur due to bone metastases between 01/01/2000 and 31/12/2023 with IMN or THA or HHA or MegaTHA or Mega. After pre-screening the databases of the respective sites, the investigators expect to find approximately a total of 600 patients. A review will be made from the medical records, radiological imaging, and histological data of partecipants.

Interventions

OTHERAnalysis

Analysis and review of imaging and clinical data

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Male and female adult patients surgically treated between 01/01/2000 and 31/12/2023 in Rizzoli Orthopaedic Institute and in Massachusetts General Hospital. * Age ≥18 y (at the time of surgery) * Patients with impending or pathological fracture due to bone metastases of the proximal femur (head/neck, intertrochanteric, subtrochanteric area). * Patients who underwent either IMN or THA or HHA or Mega or MegaTHA. * Patients with available clinical and imaging data.

Exclusion criteria

* Patients with pathological or impending fracture of proximal femur due to primary bone tumor.

Design outcomes

Primary

Measure	Time frame	Description
Analysis of implant survival	through study completion, an average of 1 year	Assess the longevity associated with the different surgical treatments used for proximal femur bone metastases.
Analysis of complications	At baseline ( T0)	Assess the post-operative complications associated with the different surgical treatments used for proximal femur bone metastases.
Analysis of functional score	1 year	Assess the functional score associated with the different surgical treatments used for proximal femur bone metastases.

Countries

Italy

Contacts

Primary ContactCostantino Errani, MD

costantino.errani@ior.it0516366

Backup ContactRoberta Laranga, PhD

roberta.laranga@ior.it0516366

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026