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The Severity Assessment Model for AECOPD With Combination of Disease and Syndrome

Construction and Evaluation of the Severity Assessment Model for AECOPD With Combination of Disease and Syndrome Based on Machine Learning

Status
Not yet recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06918353
Enrollment
1500
Registered
2025-04-09
Start date
2025-04-01
Completion date
2028-12-31
Last updated
2025-04-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute Exacerbation of Chronic Obstructive Pulmonary Disease

Keywords

Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Severity Assessment Model, Combination of Disease and Syndrome, Classification and Regression Trees, Artificial Neural Network

Brief summary

The establishment of the AECOPD severity assessment model can quickly and accurately evaluate the condition, which is of great significance for standardizing diagnosis and treatment, improving efficacy, and improving prognosis. At the same time, it can provide ideas and methods for the research of disease assessment models in related fields.

Detailed description

Accurate assessment of the condition is the prerequisite and basis for standardized clinical treatment. Traditional Chinese medicine has shown good efficacy and advantages in treating AECOPD, but currently there is no ideal standard for judging the severity, nor is there an accurate, practical, and TCM specific disease assessment tool. Therefore, this project integrates multidimensional variables of traditional Chinese and Western medicine, and intends to conduct research on the construction of a disease syndrome combined AECOPD disease assessment model through literature review, expert consultation, clinical investigation, and machine learning algorithms, and establish preliminary grading standards for the severity of AECOPD disease. Ultimately, it provides ideas and methods for the rapid and accurate assessment of AECOPD, standardized diagnosis and treatment, improved efficacy, improved prognosis, and research on disease assessment models in related fields.

Interventions

DIAGNOSTIC_TESTDiagnosis and Severity Grading of AECOPD Disease

Diagnosis and severity grading of AECOPD disease, as well as assessment of traditional Chinese medicine syndromes

Sponsors

The First Affiliated Hospital of Henan University of Traditional Chinese Medicine
CollaboratorOTHER
Henan Provincial People's Hospital
CollaboratorOTHER
Third Affiliated Hospital of Henan University of Traditional Chinese Medicine
CollaboratorOTHER
Jiangsu province hospital of TCM
CollaboratorUNKNOWN
Qingdao Traditional Chinese Medicine Hospital(Qingdao Hiser Hospital)
CollaboratorUNKNOWN
Xiangyang Traditional Chinese Medicine Hospital
CollaboratorUNKNOWN
Yanshi People's Hospital of Luoyang City
CollaboratorUNKNOWN
Shangcai County Traditional Chinese Medicine Hospital
CollaboratorUNKNOWN
Henan University of Traditional Chinese Medicine
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Meets AECOPD diagnostic criteria. * Voluntarily participate in the research and sign the consent form

Exclusion criteria

* Individuals with severe mental disorders and cognitive impairments who are unable to communicate normally

Design outcomes

Primary

MeasureTime frameDescription
Clinical Investigation Questionnaire on Influencing Factors of the Severity of AECOPD24 hoursThe influencing factors of the severity of AECOPD were evaluated through clinical investigation questionnaires. Questionnaire Title: Clinical Investigation Questionnaire on Influencing Factors of AECOPD Severity. The questionnaire adopts the scoring method, which is divided into very unimportant, not important, average, important and very important, and the corresponding values are assigned as 1, 2, 3, 4 and 5 respectively.The higher the score is, the more significant the result is.

Countries

China

Contacts

Primary ContactHailong H Zhang, doctor
zhanghailong6@126.com+86-0371-66248624

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 11, 2026