PET / CT, Prostate Cancer Metastatic Disease
Conditions
Brief summary
Investigators retrospectively collected data from consecutive patients treated at the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China, from October 2020 to March 2024. The inclusion criteria were as follows: (1) patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information; (2) patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment. The exclusion criteria were as follows: (1) patients who received novel hormone therapy or a prostate biopsy prior to PET/CT; (2) patients with other malignancies; (3) patients received hormone therapy without NHT; (4) patients received chemotherapy or radiotherapy prior to or during novel hormone therapy; (5) absence of follow-up data at the hospital.
Interventions
None listed
Sponsors
Sun Yat-sen University
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
MALE
Healthy volunteers
No
Inclusion criteria
* patients with diagnosis of metastatic hormone-sensitive prostate cancer, confirmed by PSA levels, radiographic tests and pathological information * patients who underwent FDG and PSMA PET/CT prior to the initiation of medical treatment
Exclusion criteria
* patients who received novel hormone therapy or a prostate biopsy prior to PET/CT * patients with other malignancies * patients received hormone therapy without novel hormone therapy * patients received chemotherapy or radiotherapy prior to or during novel hormone therapy * absence of follow-up data at our institution
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Castration-Resistant Prostate Cancer free survival (CRPC-FS) | From date of the initiation of novel hormone therapy until the date of first documented either PSA or radiography-confirmed progression or date of the last follow-up for any cause, whichever came first, assessed up to 100 months |
Countries
China
Outcome results
None listed