Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation (DOHECOV)

Hepatic Doppler to Assess Venous Congestion During Invasive Mechanical Ventilation

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06914336

Acronym

DOHECOV

Enrollment

100

Registered

2025-04-06

Start date

2025-03-24

Completion date

2028-10-31

Last updated

2025-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Congestion, Venous

Brief summary

The purpose of the study is to investigate venous congestion using hepatic vein doppler for ICU patients with invasive mechanical ventilastion. The primary outcome is the systolic to diastolic hepatic vein velocity ratio S/D . The objective is to find a significant association between S/D and different congestion indicators.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* intubated for more than 24 hours

Exclusion criteria

* Chronic end-stage renal disease on admission * Atrial Fibrillation * Cirrhosis * Portal thrombosis * Refusal to participate * non-opposition could not be obtained from themselves or their trusted support person in the event of incapacity * Under legal protection.

Design outcomes

Primary

Measure	Time frame	Description
Systolic to diastolic hepatic vein velocity ratio S/D	24 hours after intubation and after every 48 hours until extubation up to 12 weeks	Relate S/D ratio to clinical data on venous congestion: input/output balance, weight variation, renal insufficiency, diuresis, edema.

Countries

France

Contacts

Primary ContactGwenael PRAT, phD

gwenael.prat@chu-brest.fr0298347181

Backup ContactHamza CHRAIBI, phD

hamza.chraibi@chu-brest.fr0298347181

Outcome results