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Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Endovascular Management of CLI

Ultrasound-Guided Sciatic Popliteal Nerve Block vs. Erector Spinae Plane Block in Patients Undergoing Endovascular Management of Critical Lower Limb Ischemia

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06913348
Enrollment
70
Registered
2025-04-06
Start date
2024-03-20
Completion date
2025-01-05
Last updated
2025-04-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Limb Ischemia (CLI), ESPB, Popliteal Nerve Block

Keywords

popliteal nerve block, ESPB

Brief summary

Comparison of popliteal sciatic nerve block and erector spinae plane block (ESPB) in patients undergoing endovascular management of critical lower limb ischemia (CLI).

Detailed description

Nerve blocks, particularly regional anesthesia techniques, have been increasingly used in the endovascular management of critical lower limb ischemia (CLI). These techniques offer numerous advantages over general and local anesthesia. Primary Advantages of Nerve Blocks: 1. Superior Pain Control Nerve blocks, such as femoral and sciatic nerve blocks, provide effective pain relief by anesthetizing the nerve supply to the lower limb. They offer more comprehensive analgesia than local anesthesia alone, as they numb the entire area around the puncture site. 2. Enhanced Patient Comfort Nerve blocks allow patients to remain pain-free during and after the procedure. They minimize discomfort even in lengthy or complex cases. 3. Reduction in Systemic Analgesic Requirements By providing localized anesthesia, nerve blocks significantly reduce the need for systemic analgesics, particularly opioids. This is essential because CLI patients often have comorbidities that make opioid use risky. 4. Fewer Opioid-Related Side Effects Nerve blocks reduce the incidence of opioid-related side effects, including nausea, vomiting, respiratory depression, and sedation. 5. Improved Hemodynamic Stability Nerve blocks preserve autonomic nervous system function, reducing fluctuations in blood pressure and heart rate compared to general anesthesia. This is especially beneficial for CLI patients, who frequently have underlying cardiovascular disease.

Interventions

Procedure/Surgery: Patients will receive either an ultrasound-guided sciatic popliteal nerve block or an ultrasound-guided erector spinae plane block for anesthesia during endovascular management of critical lower limb ischemia.

Sponsors

Minia University Hospital
Lead SponsorOTHER

Study design

Observational model
OTHER
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
20 Years to 70 Years
Healthy volunteers
No

Inclusion criteria

1. Patient age will be 20-70 years. 2. Patients will be diagnosed with critical lower limb ischemia by clinical presentations and investigations. 3. ASA physical status 2-3

Exclusion criteria

1. Patient refusal to participate in this study. 2. Patient inability to understand the scales or to describe to the investigators. 3. Coagulation disorder. 4. Sever renal or kidney dysfunction. 5. Taking opioids before admission. 6. Morbid obesity .

Design outcomes

Primary

MeasureTime frameDescription
Block qualityBaseline (immediately after block administration).Assessment of the occurrence of complete motor and sensory block.

Secondary

MeasureTime frameDescription
Postoperative Analgesia DurationUp to 24 hours postoperatively.Time from block administration to the first request for rescue analgesia. .

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026