Factors Affecting Outcomes of Using Diode Laser Both 980 nm Wave Length and 450 Wavelength on Benign Laryngeal Lesions in Comparison to Traditional Cold Instrumentations as Regard Parameters of Laser Device, Nature of Lesion and Patient Factors

Factors Affecting the Outcomes of Using the Diode Laser in Benign Laryngeal Lesions

Status

Enrolling by invitation

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT06912945

Acronym

LASER

Enrollment

108

Registered

2025-04-06

Start date

2024-10-01

Completion date

2026-02-28

Last updated

2025-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benign Laryngeal Lesion

Keywords

diode, benign, laryngeal, laser

Brief summary

Studying the different Factors affecting the outcomes of using diode laser both 980 nm wave length and 450 wavelength on benign laryngeal lesions in comparison to traditional cold instrumentations

Interventions

PROCEDUREusing diode laser 980nm wavelength in benign laryngeal lesions

using diode laser 980nm wavelength in treatment of benign laryngeal lesions

PROCEDUREusing diode laser 450nm wavelength in benign laryngeal lesions

using diode laser 450nm wavelength in treatment of benign laryngeal lesions

PROCEDUREusing traditional cold instrumentations in benign laryngeal lesions

using traditional cold instrumentations in treatment of benign laryngeal lesions

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

TREATMENT

Masking

DOUBLE (Subject, Outcomes Assessor)

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

\- All patients with benign laryngeal lesions

Exclusion criteria

* patients presenting with or have history of malignant laryngeal lesion

Design outcomes

Primary

Measure	Time frame	Description
change in voice handicap index Arabic version (VHI-Arabic)	2 months after treatment	change in Voice handicap index Arabic version from baseline before treatment and after treatment
change in voice acoustic analysis	2 months after treatment	change in voice acoustic analysis including change in jitter and shimmer values from baseline preoperative and 2 months after treatment

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026