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Accuracy of Current Techniques in Quantifying Ketone Levels

Accuracy of Current Techniques in Quantifying Ketone Levels

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06909331
Enrollment
16
Registered
2025-04-03
Start date
2019-01-15
Completion date
2019-12-15
Last updated
2025-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placebo - Control, Exogenous Ketone Salt

Brief summary

The purpose of this study is to determine the accuracy of current measuring techniques used to detect physiological ketone levels.

Interventions

DIETARY_SUPPLEMENTExogenous ketone salt

Exogenous ketone salt supplement will be taken once to determine acute circulating levels of beta-hydroxybuyrate and acetoacetate compared to a control supplement.

DIETARY_SUPPLEMENTPlacebo drink solution

Participants consumed a placebo drink that was flavor, color and calorie matched to the experimental drink.

Sponsors

Augusta University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)

Eligibility

Sex/Gender
ALL
Age
18 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* 18-35 years

Exclusion criteria

* taking medications that affect blood pressure, insulin, or renal function, having meta-bolic syndrome factors such as type 2 diabetes, being pregnant, and/or indicating a pre-existing health condition on the health history questionnaire

Design outcomes

Primary

MeasureTime frameDescription
Circulating beta-hydroxybutyrate30 minutes after consuming the drinkCirculating beta-hydroxybutyrate levels measured by ketone meters and GC/MS
Circulating acetoacetate levels30 minutes after consuming the drink

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026