Skip to content

Effects of Eccentric Training in the Rehabilitation of Patients Undergoing Anterior Cruciate Ligament Reconstruction: a Randomized Controlled Trial

Effects of Eccentric Training in the Rehabilitation of Patients Undergoing Anterior Cruciate Ligament Reconstruction: a Randomized Controlled Trial

Status
Recruiting
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06905691
Enrollment
34
Registered
2025-04-01
Start date
2025-03-01
Completion date
2026-12-31
Last updated
2025-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anterior Cruciate Ligament Reconstruction Rehabilitation, Anterior Cruciate Ligament Reconstruction

Keywords

Knee, Physiotherapy, Quadriceps, Anterior cruciate ligament reconstruction, Eccentric Exercise, Eccentric

Brief summary

This study aims to investigate the effects of eccentric training on the functional rehabilitation of patients undergoing Anterior Cruciate Ligament Reconstruction (ACL-R). Thirty-four participants undergoing ACL-R will be randomly assigned to two groups: the Conventional Training Group (CTG) and the Eccentric Training Group (ETG). Both groups will adhere to the same post-surgical rehabilitation program, commencing in the first week after ACL-R and continuing until the criteria for sports resumption are achieved. The rehabilitation program will be structured into four phases: immediate post-operative, preparatory, general acquisition, and specific acquisition. The key distinction between the groups lies in their exercise regimen: ETG will prioritize the eccentric phase of movement, whereas CTG will engage in conventional exercises, maintaining uniform load across both movement phases. Assessment procedures will be conducted at three intervals for all participants: immediately post-operative, at 12 weeks post-ACL-R surgery (before the initiation of the training protocol), and at 25 weeks post-ACL-R surgery (upon completion of the training protocol). The primary outcome measure will be the maximum isometric strength of knee extensors. Secondary outcomes will encompass functional status, maximum isometric strength of knee flexors, peak dynamic strength during leg press, quadriceps muscle atrophy, performance in jump tests, and psychological readiness.

Interventions

OTHERConventional Training

Patients will execute the concentric and eccentric phases unilaterally, maintaining consistent load levels, with each phase lasting 2 seconds.

The concentric phase will be performed bilaterally in approximately 1 second, followed by the unilateral eccentric phase lasting approximately 3 seconds.

Sponsors

Federal University of Health Science of Porto Alegre
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)

Eligibility

Sex/Gender
ALL
Age
18 Years to 40 Years
Healthy volunteers
No

Inclusion criteria

\- Individuals of both genders, aged between 18 and 40 years, scheduled for ACL reconstruction surgery during the data collection period.

Exclusion criteria

* Delay of more than 7 days after surgery to initiate the rehabilitation program proposed by the study; * Presence of injuries related to the rupture of the ACL that hinder partial weight-bearing in the first week after surgery, either due to medical recommendation or the patient inability/disposition.

Design outcomes

Primary

MeasureTime frameDescription
Maximal isometric strength of knee extensorsIn the 12th and 25th weeks post-surgeryAssessed by manual isometric dynamometry

Secondary

MeasureTime frameDescription
Maximum isometric strength of knee flexorsIn the 12th and 25th weeks post-surgeryAssessed by manual isometric dynamometry
Maximum dynamic strength during leg press exerciseIn the 12th and 25th weeks post-surgeryAssessed through the 1 maximum repetition test (1RM)
Muscle atrophyIn the 12th and 25th weeks post-surgeryThe evaluation of muscle atrophy will be performed by measuring the circumference of the thigh (cm)
Self-reported functional impairmentsIn the 12th and 25th weeks post-surgery.Self-reported functional impairments will be assessed using the International Knee Documentation Committee (IKDC)
Performance in jump testsIn the 12th and 25th weeks post-surgeryMeasured through the Single and Triple Hop Tests
Psychological readiness to return to sportIn the 12th and 25th weeks post-surgery.Assessed by Return to Sport after Anterior Cruciate Ligament Reconstruction Surgery (RSI-ACL)

Countries

Brazil

Contacts

Primary ContactGabriela Bissani Gasparin
gabriela.gasparin@hotmail.com+5554991296689

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026