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Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation

Transient Pseudohypoaldosteronism Affecting Children With Urinary Tract Malformation: Diagnosis and Management in a French Retrospective Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06905600
Acronym
TPHA
Enrollment
50
Registered
2025-04-01
Start date
2024-01-31
Completion date
2025-12-31
Last updated
2025-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pseudohypoaldosteronism

Keywords

Pseudohypoaldosteronism, pseudohypoaldosteronism in children

Brief summary

Pseudohypoaldosteronism is a pathology affecting children under 6 months of age, little known but which can have serious consequences. There are no real figures on the prevalence of this pathology in France. The exact pathophysiology is not known and the management is not currently codified. This is why it is interesting to study this pathology and its treatment on a national scale in order to think about the best possible treatment, as well as to raise awareness of this pathology among different health professionals.

Interventions

None listed

Sponsors

University Hospital, Strasbourg, France
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
1 Years to 6 Years
Healthy volunteers
No

Inclusion criteria

* Minor subjects aged less than 6 years at the time of diagnosis * Diagnosis of pseudohypoaldosteronism in the context of urinary malformation and/or urinary infection between January 1, 2018 and December 31, 2023 * Subject (and/or their parental authority) having not expressed, after information, their opposition to the reuse of their data for the purposes of this research.

Exclusion criteria

* Subject (or their parents) having expressed their (their) opposition to participating in the study

Design outcomes

Primary

MeasureTime frameDescription
National comparison of clinical and therapeutic practices concerning the management of pseudohypoaldosteronism in children with urinary malformations and/or urinary infectionsUp to 1 yearThis study compares clinical and therapeutic practices The retrospective analysis of the data will be carried out using classic statistical tests (Student's test, Fisher's test, ROC curve)

Countries

France

Contacts

Primary ContactAriane ZALOSZYC, MD
ariane.zaloszyc@chru-strasbourg.fr33 3 88 12 77 42

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026