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The Effect of Salpingectomy Operation on Ovarian Reserve

Evaluation of the Effect of Salpingectomy Operation on Ovarian Reserve With Anti-Mullerian Hormone and Ovarian Doppler Ultrasonography

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06903650
Enrollment
31
Registered
2025-03-31
Start date
2020-10-27
Completion date
2021-06-05
Last updated
2025-04-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ovarian Insufficiency

Keywords

Salpingectomy, Ovarian Reserve, Anti-Mullerian Hormone, Doppler Ultrasonography

Brief summary

This study aimed to evaluate the effect of salpingectomy operation on ovarian reserve. Ovarian reserve was evaluated by measuring anti-mullerian hormone levels from serum samples taken from the patients before the operation and 6 weeks after the operation. Ovarian doppler flow were evaluated by measuring the ovarian artery pulsatility index with transvaginal ultrasonography preoperatively, postoperative days 2 and postoperative weeks 6 . In our study, it was determined that ovarian functions may be negatively affected in the acute period after salpingectomy operation.

Interventions

PROCEDUREbilateral salpingectomy, ovarian arter doppler ultrasonography

The effect of salpingectomy operation on ovarian reserve

Sponsors

Dokuz Eylul University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
37 Years to 45 Years
Healthy volunteers
Yes

Inclusion criteria

1. Women between the ages of 37-45 with continuing menstrual cycles (37 and 45 included) 2. Patients who will undergo uterine surgery for benign reasons or who will undergo salpingectomy only due to hydrosalpinx, ectopic pregnancy, tubo-ovarian abscess 3. Patients who have not had ovarian surgery before 4. Those without menopause and premature ovarian failure 5. Patients who accept the study

Exclusion criteria

1. Age younger than 37 or older than 45 2. Those who want to withdraw from the study 3. Those who do not come for follow-up examination 4. Use of drugs that affect ovarian reserve 5. Any surgical procedure performed on the ovaries during the operation 6. No menstrual bleeding in the last year 7. Patients who received radiotherapy and hormonal therapy within 3 months before surgery

Design outcomes

Primary

MeasureTime frameDescription
right ovarian arter pıperioperative, postoperative days 2 , postoperative weeks 6rate of 0,87/ 0,84/ 0,76
left ovarian arter pıperioperative, postoperative days 2, postoperative weeks 6rate of 0,89/ 0,79/ 0.80
AMH levelsperioperative-postoperative weeks 6Concentration of 1 ng/mL / 0,79 ng/mL

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026