TAP Block
Conditions
Keywords
TAP block, laparoscopic cholecistectomy
Brief summary
The goal of this clinical trial is to learn if the regional anesthesia technique TAP block provide more analgesia when performed before or after the surgery. The main questions it aims to answer are: Does preoperative TAP block provide greater analgesia than postoperative TAP block? Patients receiving preoperative TAP block will have less pain and take less painkillers than patients receiving postoperative TAP block? Participants will: Receive preoperative or postoperative TAP block They will be asked about their pain levels during the hospital stay.
Detailed description
The TAP block is a safe, easy-to-perform, and effective technique for managing postoperative pain. It reduces opioid consumption and increases patient satisfaction. Despite recent studies indicating that postoperative TAP block might be more effective than preoperative TAP block in reducing opioid use within 24 hours, the optimal timing of its administration (before or after surgery) remains unclear. In this study we will compare preoperative to postoperative TAP block in patients undergoing laparoscopic cholecistectomy. The primary aim of this study is to determine the difference in postoperative pain control between preoperative and postoperative TAP block administration in patients undergoing laparoscopic cholecystectomy. The primary objective will be to evaluate the difference in postoperative pain at rest, 24 hours after surgery, between patients receiving preoperative versus postoperative TAP block. Pain will be assessed using the Numeric Rating Scale (NRS) from 0 to 10. Secondary objectives will be intraoperative and postoperative opioids, postoperative nausea and vomiting, pain at resnt and on movement at 0,6,12,24 hours.
Interventions
PROCEDUREPreoperative TAP Block
Patients will receive preoperative TAP block
PROCEDUREPostoperative TAP block
Patients will receive postoperative TAP block
Sponsors
University of Padova
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Masking description
Participant will be masked as the intervention (TAP block) will be performed after induction of general anesthesia Outcome assessor will be unaware of the group assignment
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* ASA I-II patients * Age \>18 years * Informed consent
Exclusion criteria
* History of chronic pain * Beta-blocker therapy * Allergy to the drugs used in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Patient reported pain on movement at 24 hours after the surgery | At the 24th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Patient reported pain on rest at the end of the surgery | At the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Patient reported pain on rest at 6 hours after the surgery | At the 6th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Patient reported pain on movement at 6 hours after the surgery | At the 6th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Patient reported pain on rest at 12 hours after the surgery | At the 12th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Patient reported pain on movement (cough) at the end of the surgery | At the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Patient reported pain on rest at 24 hours after the surgery | At the 24th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
| Difference in intraoperative opioids | From the enrollment to the extubation | Difference in intraoperative fentanest in micrograms |
| Difference in postoperative opioids | From the extubation to the 24th postoperative hours | Difference in postoperative morphine in milligrams |
| Number of participants experiencing postoperative nausea and vomiting | From extubation to the 24th postoperative hour | Patients will be asked to report nausea and or vomiting in the postoperative period |
| Patient reported pain on movement at 12 hours after the surgery | At the 12th hour after the end of the surgery. | Pain will be assessed with the 11 points NRS scale (0-10) |
Countries
Italy
Contacts
Primary ContactSilvia De Pinto, MD
Outcome results
None listed