ERCP, Pancreatic Duct Stenting, Pediatric Surgery, Surgery in Early Childhood
Conditions
Keywords
pancreatic duct stones, ERCP, Frey surgery
Brief summary
The goal of this observational study is to evaluate the long-term effects of ERCP and surgery in pediatric patients with pancreatic duct stones. The main objective is to determine the optimal treatment choice(ERCP or surgery) for children with pancreatic duct stones and identify the appropriate timing for surgery in patients who have undergone multiple ERCP procedures, in order to avoid adverse outcomes caused by repeated trauma to the duodenal papilla. Last updated on January 24, 2025.
Interventions
PROCEDUREERCP
There are two intervention methods for pediatric pancreatic duct stones. One is to remove the pancreatic duct stones through Endoscopic Retrograde Cholangiopancreatography(ERCP), while simultaneously dilating the pancreatic duct and placing a stent to assist in the normal drainage of pancreatic juice. The other is local resection of the pancreatic head combined with longitudinal pancreaticojejunostomy (Frey surgery).
Sponsors
Yifan Deng
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
2 Months to 18 Years
Healthy volunteers
No
Inclusion criteria
* Patients aged 0 to 18 years * Diagnosed with pancreatic duct stones by imaging (e.g., ultrasound, CT, MRCP) * Treated and followed at pediatric surgery, west china hospital, between 2014 and 2025 * Complete clinical data available for review
Exclusion criteria
* Pancreatic duct stones secondary to previous pancreatic or biliary surgery * Concurrent severe systemic diseases (e.g., advanced cardiac, renal, or hepatic disease) * Incomplete or missing key clinical records
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| stone clearance | From intervention to the end of treatment at 1 week | The stone clearance rate refers to the proportion of patients confirmed by postoperative imaging (MRCP) to have no residual pancreatic duct stones. |
| complication rate | From enrollment to the end of treatment at 2 weeks | The complication rate refers to the incidence of pancreatitis following ERCP and associated procedures, as well as pancreatic fistula, bile leakage, and the necessity for prolonged drainage after the Frey procedure. |
| reintervention rate | From enrollment to the end of treatment at 1 year. | The reintervention rate refers to the proportion of patients who required additional invasive procedures (either ERCP or surgery) after the initial treatment. |
Outcome results
None listed